ArticleJournal of virology2011
Genetic elements in the VP region of porcine parvovirus are critical to replication efficiency in cell culture.
Article in Journal of virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Isolation, characterization, and phylogenetic analysis of two new porcine parvovirus 1 isolates from Northern China.Virus research · 2024Article
- Viral Fitness and Antigenic Determinants of Porcine Parvovirus at the Amino Acid Level of the Capsid Protein.Journal of virology · 2022Article
- Molecular epidemiology of Porcine Parvovirus Type 1 (PPV1) and the reactivity of vaccine-induced antisera against historical and current PPV1 strains.Virus evolution · 2022Article
- Capsid Proteins Are Necessary for Replication of a Parvovirus.Journal of virology · 2021Article
- Biology of Porcine Parvovirus (Ungulate parvovirus 1).Viruses · 2017Review
- Perspectives on the Evolution of Porcine Parvovirus.Viruses · 2017Article
- Rapid and specific detection of porcine parvovirus using real-time PCR and high resolution melting (HRM) analysis.BMC veterinary research · 2015Article
- Complete genome sequence of a porcine parvovirus strain isolated in central china.Genome announcements · 2014Article
- Genome sequence of Chinese porcine parvovirus strain PPV2010.Journal of virology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Factors controlling porcine parvovirus (PPV) replication efficiency are poorly characterized. Two prototype strains of PPV, NADL-2 and Kresse, differ greatly in pathogenic capacity both in vivo and in vitro, yet their genomic sequence is nearly identical (13 single-nucleotide substitutions and a 127-nucleotide noncoding repeated sequence). We have created a series of chimeras of these strains to identify the genetic elements involved in replication efficiency in the host porcine cell line. While the capsid proteins ultimately determine viral replication fitness, interaction between the NS1 protein and the VP gene occurs and involves interaction with the noncoding repeated sequence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.