Metformin × body weight & composition

TrialDiabetes2011

Effects of metformin on body weight and body composition in obese insulin-resistant children: a randomized clinical trial.

Jack A Yanovski et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 100 people · 2011

Randomised comparison

Probably lowered body weight & composition

−3.38kg−5.20 to −1.57

As reported

difference −3.38 kg, 95% CI −5.20 to −1.57

Randomised comparison

Probably lowered body weight & composition

−0.07−0.12 to −0.01

As reported

difference −0.07, 95% CI −0.12 to −0.01

Randomised comparison

Probably lowered body weight & composition

−1.40kg−2.74 to −0.06

As reported

difference −1.40 kg, 95% CI −2.74 to −0.06

Three numbers in the abstract

the abstract, start to end

P = 0.006), body weight (difference -3.38 kg, CI -5.2 to -1.57, P < 0.001), BMI Z score (difference between metformin and placebo groups -0.07, CI -0.12 to -0.01, P = 0.02), and fat mass (difference -1.40 kg, CI -2.74 to -0.06, P =

← favours treatmentfavours comparator →
could be chance
Body weight & composition
−3.38−5.20 to −1.57
Body weight & composition
−0.07−0.12 to −0.01
Body weight & composition
−1.40−2.74 to −0.06
MetforminBody weight & composition

Metformin × body weight & compositionhelps?mixed

unlikelylikely
0.500.50 without it
← favours treatmentfavours comparator →
this papermore certainless certain
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Full record →Abstract, authors, funding and every citing paper · PMID 21228310