Trial reportEuropean journal of applied physiology2011
Venous occlusion plethysmography versus Doppler ultrasound in the assessment of leg blood flow during calf exercise.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Intensity-dependent effect of ageing on fatigue during intermittent contractions of the human calf muscle in males and females.European journal of applied physiology · 2015Trial
- Skeletal muscle microvascular perfusion responses to cuff occlusion and submaximal exercise assessed by contrast-enhanced ultrasound: The effect of age.Physiological reports · 2020Article
- Cuff inflation time significantly affects blood flow recorded with venous occlusion plethysmography.European journal of applied physiology · 2019Article
- A Comparison of Muscle Sympathetic Nerve Activity to Non-contracting Muscle During Isometric Exercise in the Upper and Lower Limbs.Frontiers in neuroscience · 2019Article
- Methods for the determination of skeletal muscle blood flow: development, strengths and limitations.European journal of applied physiology · 2018Review
- Perfusion dynamics assessment with Power Doppler ultrasound in skeletal muscle during maximal and submaximal cycling exercise.European journal of applied physiology · 2018Article
- Lack of age-specific influence on leg blood flow during incremental calf plantar-flexion exercise in men and women.European journal of applied physiology · 2018Article
- Effect of obesity on oxygen uptake and cardiovascular dynamics during whole-body and leg exercise in adult males and females.Physiological reports · 2018Article
- Venous occlusion plethysmography vs. Doppler ultrasound in the assessment of leg blood flow kinetics during different intensities of calf exercise.European journal of applied physiology · 2018Article
- Blood pressure and calf muscle oxygen extraction during plantar flexion exercise in peripheral artery disease.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Article
- Muscle oxygenation during dynamic plantar flexion exercise: combining BOLD MRI with traditional physiological measurements.Physiological reports · 2016Article
- Contributions of Central Command and Muscle Feedback to Sympathetic Nerve Activity in Contracting Human Skeletal Muscle.Frontiers in physiology · 2016Article
- Interactive effect of acute sympathetic activation and exercise intensity on the dynamic response characteristics of vascular conductance in the human calf muscle.European journal of applied physiology · 2015Article
- Training Status as a Marker of the Relationship between Nitric Oxide, Oxidative Stress, and Blood Pressure in Older Adult Women.Oxidative medicine and cellular longevity · 2015Article
- Cardiovascular control during exercise in type 2 diabetes mellitus.Journal of diabetes research · 2015Review
- Effect of contraction intensity on sympathetic nerve activity to active human skeletal muscle.Frontiers in physiology · 2014Article
- Brachial artery reactivity in patients with severe sepsis: an observational study.Critical care (London, England) · 2012Article
- Dynamic response characteristics of hyperaemia in the human calf muscle: effect of exercise intensity and relation to electromyographic activity.European journal of applied physiology · 2012Article
- Resting blood flow in the skin: does it exist, and what is the influence of temperature, aging, and diabetes?Journal of diabetes science and technology · 2012Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study explored the accuracy with which venous occlusion plethysmography (VOP) assesses the hyperaemic response during calf exercise. Using Doppler ultrasound (DU) as a criterion standard technique, we tested the hypotheses that leg blood flow during contraction is not greater than at rest and that VOP provides similar estimates of the hyperaemic response between contractions as DU. Eleven subjects performed several bouts of calf exercise across a wide range of forces (50-400 N ≅ 6-45%MVC). Each bout consisted of 2 min of intermittent contractions preceded and immediately followed by sustained (40 s) contractions. DU estimates of leg blood flow during the sustained contractions were never significantly greater (P > 0.05) than those measured at rest. Paired (DU and VOP) estimates of leg blood flow (n = 488) were obtained between intermittent contractions and ranged between ~50-900 ml min(-1). There was a strong correlation between these DU and VOP estimates (Pearson r = 0.91; P < 0.05). Ordinary least products regression analysis, with VOP as the y variable, showed a relatively small proportional bias (slope = 0.942; CI = 0.938-0.946) and fixed bias (y intercept = -13.3 ml min(-1); CI = -14.4 to -12.2 ml min(-1)) between the two measurement techniques. Since these small biases can be explained by the slight differences in vascular regions which the two techniques assess, these data suggest that VOP can accurately assess the hyperaemic response to exercise.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.