ArticleMolecular and cellular biology1990
Phosphorylation of the ETS-2 protein: regulation by the T-cell antigen receptor-CD3 complex.
Article in Molecular and cellular biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 36 citations in OpenAlex.
- Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survival.The Journal of biological chemistry · 2012Article
- Ets-2 and C/EBP-beta are important mediators of ovine trophoblast Kunitz domain protein-1 gene expression in trophoblast.BMC molecular biology · 2007Article
- GABP factors bind to a distal interleukin 2 (IL-2) enhancer and contribute to c-Raf-mediated increase in IL-2 induction.Molecular and cellular biology · 1997Article
- ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation.The EMBO journal · 1995Article
- Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins.Molecular and cellular biology · 1995Article
- ets-1 in astrocytes: expression and transmitter-evoked phosphorylation.Molecular and cellular biology · 1995Article
- Participation of Ets transcription factors in the glucocorticoid response of the rat tyrosine aminotransferase gene.Molecular and cellular biology · 1994Article
- Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1.The EMBO journal · 1993Article
- A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells.Journal of virology · 1992Article
- Expression of a 91-kilodalton PEA3-binding protein is down-regulated during differentiation of F9 embryonal carcinoma cells.Molecular and cellular biology · 1992Article
- cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.Molecular and cellular biology · 1992Article
- PEA1 and PEA3 enhancer elements are primary components of the polyomavirus late transcription initiator element.Journal of virology · 1991Article
- Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I.Journal of virology · 1991Article
- The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins.The EMBO journal · 1991Article
- The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1.The EMBO journal · 1990Article
- Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1.Proceedings of the National Academy of Sciences of the United States of America · 1990Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phosphorylation of the human ets-2 protein in response to mitogenic signals to T lymphocytes was investigated in Jurkat cells. Activation of the cells by antibodies against the T-cell antigen receptor-CD3 complex or by concanavalin A was followed within 5 min by increased phosphorylation of the protein, as shown by a mobility shift of the protein from 54 to 56 kilodaltons in sodium dodecyl sulfate-polyacrylamide gel electrophoresis and increased incorporation of 32P. The Ca2+ ionophores A23187 and ionomycin were able to mimic this effect, suggesting that this phosphorylation is mediated by Ca2+.
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