Metformin × glycemic control

TrialThe Journal of the Association of Physicians of India2010

A prospective, parallel group, open-labeled, comparative, multi-centric, active controlled study to evaluate the safety, tolerability and benefits of fixed dose combination of acarbose and metformin versus metformin alone in type 2 diabetes.

S Jayaram et al.PubMed ↗

What the trial testedas reported · 229 people · 2010

No range given

Reported lower glycemic control, no range given

−19.4mg/dl

As reported

difference −19.4 mg/dl, no interval

No range given

Reported lower glycemic control, no range given

−28.3mg/dl

As reported

difference −28.3 mg/dl, no interval

+4 more in the walkthrough ↓

Six numbers in the abstract

the abstract, start to end

of 158.85 +/- 18.14 mg/dl to 113.55 +/- 19.38 mg/dl (p < 0.0001) (decrease of 45.30 +/- 15.30 mg/dl) at 12 weeks, while in the metformin group fasting blood glucose decreased from a baseline of 158.31 +/- 26.53 mg/dl to 130.55 +/- 28.31 mg/dl (p < 0.0001) (decrease of

of 264.65 +/- 34.03 mg/dl to 173.22 +/- 31.40 mg/dl (p < 0.0001) (decrease of 91.43 +/- 28.65 mg/dl) at 12 weeks, while in the metformin group PPBG decreased from a baseline of 253.56 +/- 36.28 mg/dl to 205.36 +/- 39.49 mg/dl (p < 0.0001) (decrease of

a baseline of 9.47 +/- 0.69% to 7.71 +/- 0.85% (p < 0.0001) (% decrease of 1.76 +/- 1.11) at 12 weeks, while in the metformin group HbAlc decreased from a baseline of 9.32 +/- 0.65% to 8.26 +/- 0.68% (p < 0.0001) (% decrease of

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Glycemic control
−19.4
Glycemic control
−28.3
Glycemic control
−31.4
Glycemic control
−39.5
Glycemic control
−0.85
Glycemic control
−0.68
MetforminOther glucose-loweringGlycemic control
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