ArticlePloS one2011
Detection of head-to-tail DNA sequences of human bocavirus in clinical samples.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 69 citations in OpenAlex.
- Twenty years of human bocavirus research: from an unculturable virus of unclear pathogenicity to a culturable human pathogen and gene therapy vector candidate.Clinical microbiology reviews · 2025Review
- Diverse Head-to-Tail Sequences in the Circular Genome of Human Bocavirus Genotype 1 among Children with Acute Respiratory Infections Implied the Switch of Template Chain in the Rolling-Circle Replication Model.Pathogens (Basel, Switzerland) · 2024Article
- T84 Monolayer Cell Cultures Support Productive HBoV and HSV-1 Replication and Enable In Vitro Co-Infection Studies.Viruses · 2024Article
- Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection.Viruses · 2021Article
- Human Bocavirus infection and respiratory tract disease identified in a UK patient cohort.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020Article
- Human bocavirus in children hospitalized for acute respiratory tract infection in Rome.World journal of pediatrics : WJP · 2020Article
- Viral metagenomic analysis of chickens with runting-stunting syndrome in the Republic of Korea.Virology journal · 2020Article
- Keeping all secondary structures of the non-coding region in the circular genome of human bocavirus 2 is important for DNA replication and virus assembly, as revealed by three hetero-recombinant genomic clones.Emerging microbes & infections · 2019Article
- The Molecular Detection of Human Bocavirus (HBoV) in Colorectal Tissue with Malignant and Non-Malignant LesionsAsian Pacific journal of cancer prevention : APJCP · 2018Article
- Article
- Association of the Human Bocavirus With Tonsil Squamous Cell Carcinomas.Frontiers in microbiology · 2018Article
- Detection of human bocavirus in Saudi healthy blood donors.PloS one · 2018Article
- Genomic recombination in primate bocavirus: inconsistency and alternative interpretations.Virus genes · 2017Review
- Human bocavirus 1 infection of CACO-2 cell line cultures.Virology · 2017Article
- Fatal HBoV-1 infection in adult female cystic fibrosis patient.Human pathology (New York) · 2017Article
- Infections and coinfections by respiratory human bocavirus during eight seasons in hospitalized children.Journal of medical virology · 2016Article
- Human bocavirus: Current knowledge and future challenges.World journal of gastroenterology · 2016Review
- Latent infection of human bocavirus accompanied by flare of chronic cough, fatigue and episodes of viral replication in an immunocompetent adult patient, Cologne, Germany.JMM case reports · 2016Article
- Lung Infection by Human Bocavirus Induces the Release of Profibrotic Mediator Cytokines In Vivo and In Vitro.PloS one · 2016Article
- Case Report: Human Bocavirus Associated Pneumonia as Cause of Acute Injury, Cologne, Germany.Medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parvoviruses are single stranded DNA viruses that replicate in a so called "rolling-hairpin" mechanism, a variant of the rolling circle replication known for bacteriophages like φX174. The replication intermediates of parvoviruses thus are concatemers of head-to-head or tail-to-tail structure. Surprisingly, in case of the novel human bocavirus, neither head-to-head nor tail-to-tail DNA sequences were detected in clinical isolates; in contrast head-to-tail DNA sequences were identified by PCR and sequencing. Thereby, the head-to-tail sequences were linked by a novel sequence of 54 bp of which 20 bp also occur as conserved structures of the palindromic ends of parvovirus MVC which in turn is a close relative to human bocavirus.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.