Evidence map›Paper›PMID 21595702›Full record

ReviewParasite immunology

Genomics and population biology of Cryptosporidium species.

G Widmer, S Sullivan

Abstract readReview
In one paragraph

Review in Parasite immunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Review
  3. InvestigatingInternational journal of molecular sciences · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Food and waterborne parasitology · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Direct Sequencing ofFrontiers in public health · 2019
    Review
  13. Article
  14. Observational
  15. Genomics of apicomplexan parasites.Critical reviews in biochemistry and molecular biology · 2017
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

G WidmerDivision of Infectious Diseases, Tufts Cummins School of Veterinary Medicine, North Grafton, MA 01536, USA. giovanni.widmer@tufts.edu
S Sullivan
New York University · USTufts University · US

Funding

Genetics of Cryptosporidium parvumR01AI052781 · NIAID · TUFTS UNIVERSITY BOSTON · PI WIDMER, GIOVANNI · 2002 to 2010
$1.8M
Functional Genomics of Cryptosporidium parvumR01AI055347 · NIAID · TUFTS UNIVERSITY BOSTON · PI WIDMER, GIOVANNI · 2004 to 2007
$1.7M
Genetics of Cryptosporidium parvumR56AI052781 · NIAID · TUFTS UNIVERSITY BOSTON · PI WIDMER, GIOVANNI · 2008 to 2008
$293k
NIAID NIH HHS AI052781NIAID NIH HHS R01 AI052781NIAID NIH HHS R01 AI055347NIAID NIH HHS R56 AI052781
6 · The paper itself

Abstract

We describe recent advances in the genomics and population biology of Cryptosporidium parvum and C. hominis, the causative agents of cryptosporidiosis in humans and animals. Many basic aspects of the biology of Cryptosporidium species remain to be investigated and effective drugs to control cryptosporidiosis are not available. Sequencing and annotation of the genome of C. parvum and C. hominis has uncovered unique features of the metabolism of these species. The recently sequenced genome of the gastric species C. muris is providing new insights into the evolution of the genus. Cryptosporidian sequence information has facilitated the identification of polymorphic genetic markers. Genotyping of oocysts excreted by human and animal hosts using such markers has revealed many new species and genotypes, and is leading to a better understanding of the epidemiology of cryptosporidiosis.

Indexed as

AnimalsCryptosporidiosisCryptosporidiumGenetic MarkersGenome, ProtozoanGenomicsHumansOocystsSpecies SpecificityGenetic Markers

Identifiers

PMID21595702
PMCPMC3168714
OpenAlexW1591086665

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.