ReviewDiabetes care2011
Use of metformin in the setting of mild-to-moderate renal insufficiency.
Review in Diabetes care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 132 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Phase 3 Trial of Metformin in Patients Initiating Androgen Deprivation Therapy as Prevention and Intervention of Metabolic Syndrome: The Prime Study
Metformin Pharmacology in Human Cancers
Use of Metformin in Prevention and Treatment of Cardiac Fibrosis in PAI-1 Deficient Population
Who cites it
132 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022Guideline
- Pooled it
- Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).Diabetes care · 2012 · on this mapGuideline
- Metformin in patients with type 2 diabetes and kidney disease: a systematic review.JAMA · on this mapPooled it
- Effects of Metformin on Left Ventricular Size and Function in Hypertensive Patients with Type 2 Diabetes Mellitus: Results of a Randomized, Controlled, Multicenter, Phase IV Trial.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2020Trial
- Protocol for a randomised controlled trial of the effect of dapagliflozin, metformin and exercise on glycaemic variability, body composition and cardiovascular risk in prediabetes (the PRE-D Trial).BMJ open · 2017 · on this mapTrial
- How to improve drug dosing for patients with renal impairment in primary care - a cluster-randomized controlled trial.BMC family practice · 2012Trial
- [Geriatric aspects of diabetes mellitus (Update 2026)].Wiener klinische Wochenschrift · 2026Review
- Self-Management, Adherence, and the Role of Pharmaceutical Care in Patients with T2DM in Primary Practice: A Cross-Sectional Survey in Bulgaria.Pharmacy (Basel, Switzerland) · 2026Article
- Association is not yet an indication: concerns about monitoring claims and residual confounding in outpatient metformin-associated lactate elevation.Therapeutic advances in endocrinology and metabolism · 2026Article
- Factors potentiating risk of higher lactate level associated with metformin therapy: a cross-sectional study in an ambulatory care setting.Therapeutic advances in endocrinology and metabolism · 2026Article
- Repurposing metformin for cardioprotection: mechanisms and therapeutic potential across cardiovascular pathologies.Frontiers in pharmacology · 2026Review
- 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- The role of AMPK signaling pathway in the pathogenesis of type 2 diabetes mellitus with its complications and related metabolic disorders.Metabolism open · 2025Review
- Metformin and risk factors for chronic kidney disease in a European population based on Mendelian randomization.Renal failure · 2025Article
- Article
- 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2025.Diabetes care · 2025 · on this mapReview
- Glucagon-like peptide-1 receptor agonists in liver transplant recipients with diabetes: changes in glucose control and cardiometabolic risk factors.Frontiers in endocrinology · 2025Article
- Economic costs and medications for diabetes in older patients in Beijing, China: electronic insurance data analysis.Frontiers in pharmacology · 2025Article
- ASN Kidney Health Guidance on the Management of Obesity in Persons Living with Kidney Diseases.Journal of the American Society of Nephrology : JASN · 2024Article
72 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by[Not Available].2012
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.