Evidence map›Paper›PMID 21635713›Full record

ReviewGenome biology2011

Mapping of disease-associated variants in admixed populations.

Daniel Shriner, Adebowale Adeyemo, Edward Ramos, Guanjie Chen, Charles N Rotimi

Abstract readReview
In one paragraph

Review in Genome biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. African American ancestry contribution to asthma and atopic dermatitis.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2019
    Review
  13. Review
  14. Article
  15. Analysis of admixture proportions in seven geographical regions of the state of Guerrero, Mexico.American journal of human biology : the official journal of the Human Biology Council · 2017
    Article
  16. Article
  17. Article
  18. Article
  19. The African diaspora: history, adaptation and health.Current opinion in genetics & development · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel ShrinerCenter for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Drive, MSC 5635, Bethesda, MD 20892, USA. shrinerda@mail.nih.gov
Adebowale Adeyemo
Edward Ramos
Guanjie Chen
Charles N Rotimi

Funding

UVDM01RR010284 · NCRR · HOWARD UNIVERSITY · PI TAYLOR, WILLIAM ROBERT · 1996 to 2010
$17.4M
The Howard University SCORE Program Supplemental GrantS06GM008016 · NIGMS · HOWARD UNIVERSITY · PI LITTLETON, GEORGE K · 1989 to 2009
$16.1M
Intramural NIH HHSNCRR NIH HHS 2M01RR010284NIGMS NIH HHS S06GM008016-320107NIGMS NIH HHS S06GM008016-380111PHS HHS 1ZIAHG200362-02
6 · The paper itself

Abstract

A more refined estimation of ancestry would benefit admixture mapping and association mapping, making disease loci identification in admixed populations more powerful.

Indexed as

Genetic MarkersPopulation DynamicsAllelesAmerican Indian or Alaska NativeBlack PeopleCardiovascular DiseasesChromosome MappingGene FrequencyGenetic Predisposition to DiseaseGenetics, PopulationGenetic VariationGenomicsHumansModels, GeneticPhylogenyPolymorphism, Single NucleotideGenetic Markers

Identifiers

PMID21635713
PMCPMC3219963

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.