ArticleGastroenterology research and practice2011
Clinical Validation of an Office-Based C-UBT (Heliprobe) for H. pylori Diagnosis in Iranian Dyspeptic Patients.
Article in Gastroenterology research and practice, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Urea breath test forWorld journal of gastroenterology · 2024Pooled it
- Non-invasive diagnostic tests for Helicobacter pylori infection.The Cochrane database of systematic reviews · 2018Pooled it
- Seven-day quintuple regimen as a rescue therapy for Helicobacter pylori eradication.World journal of gastroenterology · 2015Trial
- Stool Antigen Testing, a Reliable Noninvasive Method of Assessment of Helicobacter pylori Infection Among Patients with Gastro-duodenal Disorders in Cameroon.Digestive diseases and sciences · 2021Article
- Diagnostic Value ofClinical and experimental gastroenterology · 2021Article
- Prevalence ofMedicina (Kaunas, Lithuania) · 2020Review
- Article
- Association betweenOpen access Macedonian journal of medical sciences · 2018Article
- Unique features and risk factors of Helicobacter pylori infection at the main children's intermediate school in Rabigh, Saudi Arabia.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2014Article
- Association of Helicobacter pylori infection with the Lewis and ABO blood groups in dyspeptic patients.Nigerian medical journal : journal of the Nigeria Medical Association · 2013Article
- Effect of gastric acidification on the (14)C-UBT HELIPROBE(®) accuracy during Pantoprazole treatment in Helicobacter pylori positive patients.International journal of clinical and experimental medicine · 2013Article
- Bacterial urease and its role in long-lasting human diseases.Current protein & peptide science · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. We encountered repeatedly, in our clinical practice, discordant results between UBT and histopathology about H. pylori infection. Goal. To study the diagnostic accuracy of Heliprobe (14)C-urea breath test ((14)C-UBT) for detection of H. pylori infection in an Iranian population. Study. We enrolled 125 dyspeptic patients in our study. All of them underwent gastroscopy, and four gastric biopsies (three from the antrum and one from the corpus) were obtained. One of the antral biopsies was utilized for a rapid urease test (RUT), and three others were evaluated under microscopic examination. Sera from all patients were investigated for the presence of H. pylori IgG antibodies. The (14)C-UBT was performed on all subjects using Heliprobe kit, and results were analyzed against the following gold standard (GS): H. pylori infection considered positive when any two of three diagnostic methods (histopathology, RUT, serology) are positive. Results. According to data analysis, the Heliprobe (14)C-UBT had 94% sensitivity, 100% specificity, 93% negative predictive value (NPV), 100% positive predictive value (PPV), and 97% accuracy, compared with GS. Conclusion. The Heliprobe (14)C-UBT is an easy-to-perform, rapid-response, and accurate test for H. pylori diagnosis, suitable for office use.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.