Evidence map›Paper›PMID 21841072›Full record

ReviewPhysiology (Bethesda, Md.)2011

New insights into HIV assembly and trafficking.

Muthukumar Balasubramaniam, Eric O Freed

Open access · greenAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 92 citations in OpenAlex.

  1. Proteomic Characterization of HIV Infection.Advances in experimental medicine and biology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Immune Control of HIV.Journal of life sciences (Westlake Village, Calif.) · 2019
    Article
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Muthukumar BalasubramaniamVirus-Cell Interaction Section, HIV Drug Resistance Program, National Cancer Institute, Frederick, Maryland, USA.
Eric O Freed
National Cancer Institute · US

Funding

Retroviral Gag Trafficking, Env Incorporation, and Virus AssemblyZIABC010775 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI FREED, ERIC · 2009 to 2015
$4.6M
Retroviral Gag Trafficking, Env Incorporation, and Virus AssemblyZ01BC010775 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI FREED, ERIC · 2007 to 2008
$961k
Intramural NIH HHS Z01 BC010775
6 · The paper itself

Abstract

Assembly and release of human immunodeficiency virus type 1 (HIV-1) particles is mediated by the viral Gag polyprotein precursor. Gag is synthesized in the cytosol and rapidly translocates to membrane to orchestrate particle production. The cell biology of HIV-1 Gag trafficking is currently one of the least understood aspects of HIV-1 replication. In this review, we highlight the current understanding of the cellular machinery involved in Gag trafficking and virus assembly.

Indexed as

gag Gene Products, Human Immunodeficiency VirusHIV-1HumansProtein TransportVirus Assemblygag Gene Products, Human Immunodeficiency Virus

Identifiers

PMID21841072
PMCPMC3467973
OpenAlexW2098437057

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.