ArticleCirculation1990
Coronary artery imaging with intravascular high-frequency ultrasound.
Article in Circulation, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01200056 (A Prospective, Double-blinded, Randomised Study to Evaluate the Effects of Different Doses of Statin Treatment on Plaque Volume and Composition in Coronary Disease Determined by Virtual Histology Using Intravascular Ultrasound), which is not on this map. Cited by 76 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Double-blinded, Randomised Study to Evaluate the Effects of Different Doses of Statin Treatment on Plaque Volume and Composition in Coronary Disease Determined by Virtual Histology Using Intravascular Ultrasound
Who cites it
76 citing papers in PubMed, 601 citations in OpenAlex.
- Randomised comparison of the effects of nicardipine and esmolol on coronary artery wall stress: implications for the risk of plaque rupture.Heart (British Cardiac Society) · 2000Trial
- Measuring progression and regression of coronary atherosclerosis in clinical trials: problems and progress.International journal of cardiac imaging · 1992Trial
- Advances in coronary imaging of atherosclerotic plaques.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Review
- Examination of the performance of machine learning-based automated coronary plaque characterization by near-infrared spectroscopy-intravascular ultrasound and optical coherence tomography with histology.European heart journal. Digital health · 2025Article
- A Review of Application of Deep Learning in Endoscopic Image Processing.Journal of imaging · 2024Review
- The uric acid/HDL-C ratio may predict significant coronary stenosis in moderate left main coronary artery lesions: an intravascular ultrasonography study.Lipids in health and disease · 2024Article
- A Comparison of Three-Layer and Single-Layer Small Vascular Grafts Manufactured via the Roto-Evaporation Method.Polymers · 2024Article
- Clinical expert consensus document on standards for lower extremity artery disease of imaging modality from the Japan Endovascular Treatment Conference.Cardiovascular intervention and therapeutics · 2022Article
- Coronary lipid-rich plaque characteristics in Japanese patients with acute coronary syndrome and stable angina: A near infrared spectroscopy and intravascular ultrasound study.International journal of cardiology. Heart & vasculature · 2021Article
- Intravascular Molecular Imaging: Near-Infrared Fluorescence as a New Frontier.Frontiers in cardiovascular medicine · 2020Review
- Hybrid intravascular imaging: recent advances, technical considerations, and current applications in the study of plaque pathophysiology.European heart journal · 2017Review
- A High Frequency Geometric Focusing Transducer Based on 1-3 Piezocomposite for Intravascular Ultrasound Imaging.BioMed research international · 2017Article
- Quantitative Ultrasound for Nondestructive Characterization of Engineered Tissues and Biomaterials.Annals of biomedical engineering · 2016Review
- High-frequency ultrasound analysis of post-mitotic arrest cell death.Oncoscience · 2016Article
- Feasibility of diagnosing unstable plaque in patients with acute coronary syndrome using iMap-IVUS.Journal of Zhejiang University. Science. B · 2015Article
- Ultrasound imaging for risk assessment in atherosclerosis.International journal of molecular sciences · 2015Review
- A 10-mm MR-Conditional Unidirectional Pneumatic Stepper Motor.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2015Article
- Intravascular Ultrasound Versus Optical Coherence Tomography for Coronary Artery Imaging - Apples and Oranges?Interventional cardiology (London, England) · 2015Article
- Multi-frequency intravascular ultrasound (IVUS) imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2015Article
- PMN-PT single-crystal high-frequency kerfless phased array.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2014Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Safe and effective clinical application of new interventional therapies may require more precise imaging of atherosclerotic coronary arteries. To determine the reliability of catheter-based intravascular ultrasound as an imaging modality, a miniaturized prototype ultrasound system (1-mm transducer; center frequency, 25 MHz) was used to acquire two-dimensional, cross-sectional images in 21 human coronary arteries from 13 patients studied at necropsy who had moderate-to-severe atherosclerosis. Fifty-four atherosclerotic sites imagined by ultrasound were compared with formalin-fixed and fresh histological sections of the coronary arteries with a digital video planimetry system. Ultrasound and histological measurements correlated significantly (all p less than 0.0001) for coronary artery cross-sectional area (r = 0.94), residual lumen cross-sectional area (r = 0.85), percent cross-sectional area (r = 0.84), and linear wall thickness (plaque and media) measured at 0 degrees, 90 degrees, 180 degrees, and 270 degrees (r = 0.92). Moreover, ultrasound accurately predicted histological plaque composition in 96% of cases. Anatomic features of the coronary arteries that were easily discernible were the lumen-plaque and media-adventitia interfaces, very bright echoes casting acoustic shadows in calcified plaques, bright and homogeneous echoes in fibrous plaques, and relatively echo-lucent images in lipid-filled lesions. These data indicate that intravascular ultrasound provides accurate image characterization of the artery lumen and wall geometry as well as the presence, distribution, and histological type of atherosclerotic plaque. Thus, ultrasound imaging appears to have great potential application for enhanced diagnosis of coronary atherosclerosis and may serve to guide new catheter-based techniques in the treatment of coronary artery disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.