ArticleJournal of clinical research in pediatric endocrinology2011
The relationship between metabolic syndrome and left ventricular mass index in obese children.
Article in Journal of clinical research in pediatric endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Myocardial Performance Index and Carotid Intima-Media Thickness in Children with Metabolically Healthy and Metabolically Unhealthy ObesityJournal of clinical research in pediatric endocrinology · 2026Article
- Obesity and Left Ventricular Function in American Indian Adolescents: Strong Heart Family Study.Journal of racial and ethnic health disparities · 2025Article
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study.Pediatrics · 2022Article
- Iron Metabolism in Obesity and Metabolic Syndrome.International journal of molecular sciences · 2020Review
- Cardiac function in adolescents with obesity: cardiometabolic risk factors and impact on physical fitness.International journal of obesity (2005) · 2019Observational
- Assessment of left ventricular mass index could predict metabolic syndrome in obese children.Journal of the Saudi Heart Association · 2016Article
- Left ventricular mass and diastolic function in obese children and adolescents.Pediatric nephrology (Berlin, Germany) · 2015Article
- Which metabolic syndrome criteria best predict non-alcoholic fatty liver disease in children?Eating and weight disorders : EWD · 2014Article
- Childhood obesity and autonomic dysfunction: risk for cardiac morbidity and mortality.Current treatment options in cardiovascular medicine · 2014Article
- Epicardial adiposity in children with obesity and metabolic syndrome.Iranian journal of pediatrics · 2014Article
- Detection of early diastolic alterations by tissue Doppler imaging in untreated childhood-onset essential hypertension.Journal of the American Society of Hypertension : JASH · 2014Article
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Authors and funding
4 authors.
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Abstract
objectiveTo investigate the relationships between metabolic syndrome (MS), other metabolic features and left ventricular mass index (LVMI) in a population of obese children and adolescents with MS.
methodsTwo hundred and eight obese children and adolescents (119 females and 89 males, mean age: 11.9±2.7 years) and control subjects (24 females and 26 males, mean age: 11.4±2.9 years) were enrolled in the study. The insulin sensitivity index and LVMI were determined. The International Diabetes Federation criteria were used to diagnose MS.
resultsThe obese patients were divided into MS group (n=55) and non-MS (n=153) group. The values of LVMI in the MS group were significantly higher than those in the non-MS group (p=0.014). The present LVMI cut-off point of 33 g/m² for the diagnosis of MS yielded a sensitivity of 97% and a specificity of 98%. LVMI was found to be positively correlated in univariate analysis with height, weight, body mass index (BMI) SDS, fasting insulin level, homeostasis model assessment of insulin resistance (HOMA-IR) and fasting glucose to insulin ratio (FGIR) and negatively correlated with quantitative insulin sensitivity check index (QUICK-I).
conclusionsWe suggest that our optimal LVMI cut-off value for identifying MS may be considered as a sensitive index in screening obese children and adolescents for pediatric MS. Assessment of LVMI in obese children and adolescents may be used as a tool in predicting the presence of MS and its associated cardiovascular risks.
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