Trial reportEuropean journal of applied physiology2012
Resistance exercise and aerobic exercise when paired with dietary energy restriction both reduce the clinical components of metabolic syndrome in previously physically inactive males.
Trial report in European journal of applied physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03355469 (Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome), which is not on this map. Cited by 19 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome
Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Pooled it
- Comparing exercise modalities during caloric restriction: a systematic review and network meta-analysis on body composition.Frontiers in nutrition · 2025Pooled it
- Association between sedentary behavior, physical activity, and cardiovascular disease-related outcomes in adults-A meta-analysis and systematic review.Frontiers in public health · 2022Pooled it
- Impact of different training modalities on anthropometric outcomes in patients with obesity: A systematic review and network meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Pooled it
- Pooled it
- Effects of aerobic and resistance exercises on circulating apelin-12 and apelin-36 concentrations in obese middle-aged women: a randomized controlled trial.BMC women's health · 2019Trial
- Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults: a randomized clinical trial.Journal of translational medicine · 2017Trial
- Effect of a High-Protein Energy-Restricted Diet Combined with Resistance Training on Metabolic Profile in Older Individuals with Metabolic Impairments.The journal of nutrition, health & aging · 2017Trial
- Cardiometabolic risk factor response to a lifestyle intervention: a randomized trial.Metabolic syndrome and related disorders · 2015Trial
- Effect of adiposity on insulin action after acute and chronic resistance exercise in non-diabetic women.European journal of applied physiology · 2013Trial
- Walking promotes metabolic and baroreflex sensitivity improvement in fructose-fed male rats.European journal of applied physiology · 2013Trial
- Sixteen weeks of resistance training can decrease the risk of metabolic syndrome in healthy postmenopausal women.Clinical interventions in aging · 2013Trial
- Exercise training with weight loss and either a high- or low-glycemic index diet reduces metabolic syndrome severity in older adults.Annals of nutrition & metabolism · 2012 · on this mapTrial
- Effects of 12 Weeks of Resistance Training on Body Composition, Muscle Hypertrophy and Function, Blood Lipid Level, and Hemorheological Properties in Middle-Aged Obese Women.Reviews in cardiovascular medicine · 2023Article
- The CHANGE program: Exercise intervention in primary care.Canadian family physician Medecin de famille canadien · 2017Article
- Resistance training reduces systolic blood pressure in metabolic syndrome: a systematic review and meta-analysis of randomised controlled trials.British journal of sports medicine · 2016Review
- Effect of aerobic exercise training on cardiometabolic risk factors among professional athletes in the heaviest-weight class.Diabetology & metabolic syndrome · 2015Article
- Metabolic, hemodynamic and structural adjustments to low intensity exercise training in a metabolic syndrome model.Cardiovascular diabetology · 2013Article
- Effects of eight weeks of resistance training on the risk factors of metabolic syndrome in overweight /obese women - "A Pilot Study".Diabetology & metabolic syndrome · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to compare resistance exercise training (RT) to aerobic exercise training (AE) on the clinical risk factors for metabolic syndrome (MetSyn) in physically inactive overweight males (age 27-48 years). Subjects with at least one risk factor for MetSyn performed RT (n = 13, age 35.1 ± 4.7 years, BMI 31.2 ± 2.7 kg/m(2)) or AE (n = 9, age 37.6 ± 4.9 years, BMI, 31.2 ± 3.2 kg/m(2)) for 6 months. Training frequency and exercise session duration were equal and by 3 months the subjects exercised 4 day/week for 45 min/session. Blood lipids and glucose, waist circumference, and mean arterial blood pressure (MAP) were measured at 0, 3, and 6 months. A MetSyn z score was calculated for each subject from triglycerides, HDL cholesterol, fasting glucose, waist circumference, and MAP. Statistical significance was set at p ≤ 0.05. No significant differences existed between RT and AE groups at 0 month. AE showed a significant reduction in MetSyn z score from 0 (0.91 ± 3.57) to 6 months (-1.35 ± 2.95), while RT approached significance (p = 0.07) from 0 (0.09 ± 2.62) to 6 months (-1.30 ± 2.22). Triglycerides (mmol/L) significantly decreased in AE from 0 (1.93 ± 0.90) to 6 months (1.41 ± 0.70). Waist circumference (cm) significantly decreased in AE from 0 (106.8 ± 7.3) to 6 months (101.2 ± 6.5), and in RT from 0 (108.4 ± 9.0) to 6 months (105.7 ± 7.0). MAP (mmHg) decreased in RT from 0 (93.8 ± 5.8) to 6 months (87.5 ± 6.1) and in AE from 0 (97.6 ± 7.0) to 6 months (91.3 ± 6.8). With equal training frequency and exercise session duration, both RT and AE training, when paired with energy restriction improve the clinical risk factor profile for MetSyn.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.