Evidence map›Paper›PMID 21994631›Full record

ArticleViruses2010

Hantaviruses in the americas and their role as emerging pathogens.

Brian Hjelle, Fernando Torres-Pérez

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 3 syntheses or guidelines pooled it, 124 citations in OpenAlex.

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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brian HjelleCenter for Infectious Diseases and Immunity, Department of Pathology, University of New Mexico Health Sciences Center, MSC08 4640, Albuquerque, New Mexico 87131, USA; E-Mail: ftorresp@gmail.com.
Fernando Torres-Pérez
University of New Mexico · US

Funding

Virology/Immunology CoreU19AI045452 · NIAID · UNIVERSITY OF NEW MEXICO · PI MERTZ, GREGORY JAMES · 1999 to 2009
$8.7M
Postdoctoral Training in the Hantavirus Project EcologyD43TW007131 · FIC · UNIVERSITY OF NEW MEXICO · PI MERTZ, GREGORY JAMES · 2004 to 2004
$50k
FIC NIH HHS D43 TW007131NIAID NIH HHS U19 AI045452
6 · The paper itself

Abstract

The continued emergence and re-emergence of pathogens represent an ongoing, sometimes major, threat to populations. Hantaviruses (family Bunyaviridae) and their associated human diseases were considered to be confined to Eurasia, but the occurrence of an outbreak in 1993-94 in the southwestern United States led to a great increase in their study among virologists worldwide. Well over 40 hantaviral genotypes have been described, the large majority since 1993, and nearly half of them pathogenic for humans. Hantaviruses cause persistent infections in their reservoir hosts, and in the Americas, human disease is manifest as a cardiopulmonary compromise, hantavirus cardiopulmonary syndrome (HCPS), with case-fatality ratios, for the most common viral serotypes, between 30% and 40%. Habitat disturbance and larger-scale ecological disturbances, perhaps including climate change, are among the factors that may have increased the human caseload of HCPS between 1993 and the present. We consider here the features that influence the structure of host population dynamics that may lead to viral outbreaks, as well as the macromolecular determinants of hantaviruses that have been regarded as having potential contribution to pathogenicity.

Indexed as

emergenceepidemiologyhantavirushantavirus cardiopulmonary syndromepathology

Identifiers

PMID21994631
PMCPMC3185593
OpenAlexW2128230863

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.