Trial reportBMJ (Clinical research ed.)1990
Outcome of renal replacement treatment in patients with diabetes mellitus.
Trial report in BMJ (Clinical research ed.), 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 56 citations in OpenAlex.
- Diabetes and end-stage renal disease; a review article on new concepts.Journal of renal injury prevention · 2015Review
- Long-term clinical outcomes of peritoneal dialysis patients: 9-year experience of a single center from north India.Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis · 2014Article
- Influence of vascular access type on sex and ethnicity-related mortality in hemodialysis-dependent patients.The Permanente journal · 2012Article
- Survival in dialysis patients is not different between patients with diabetes as primary renal disease and patients with diabetes as a co-morbid condition.BMC nephrology · 2011Article
- Cigarette smoking: an important renal risk factor - far beyond carcinogenesis.Tobacco induced diseases · 2002Article
- Cardiac disease in diabetic end-stage renal disease.Diabetologia · 1997Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the outcome of renal replacement treatment in patients with diabetes mellitus and in non-diabetic patients with end stage renal failure.
designRetrospective comparison of cases and matched controls.
settingRenal unit, Western Infirmary, Glasgow, providing both dialysis and renal transplantation. PATIENTS: 82 Diabetic patients starting renal replacement treatment between 1979 and 1988, compared with 82 matched non-diabetic controls with renal failure and 39 different matched controls undergoing renal transplantation.
main outcome measuresPatient characteristics, history of smoking, prevalence of left ventricular hypertrophy and myocardial ischaemia at start of renal replacement treatment; survival of patients with renal replacement treatment and of patients and allografts with renal transplantation.
resultsThe overall survival of the diabetic patients during the treatment was 83%, 59%, and 50% at one, three, and five years. Survival was significantly poorer in the diabetic patients than the controls (p less than 0.001). Particularly adverse features for outcome at the start of treatment were increasing age (p less than 0.01) and current cigarette smoking (relative risk (95% confidence interval) 2.28 (0.93 to 4.84), p less than 0.05). Deaths were mainly from cardiac and vascular causes. The incidence of peritonitis in patients on continuous ambulatory peritoneal dialysis was the same in diabetic patients and controls (49% in each group remained free of peritonitis after one year), and the survival of renal allografts was not significantly worse in diabetic patients (p less than 0.5).
conclusionsRenal replacement treatment may give good results in diabetic patients, although the outlook remains less favourable than for non-diabetic patients because of coexistent, progressive vascular disease, which is more severe in older patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.