ArticleJournal of neurogastroenterology and motility2011
Should we still subcategorize helicobacter pylori-associated dyspepsia as functional disease?
Article in Journal of neurogastroenterology and motility, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Evidence-based clinical practice guidelines for functional dyspepsia.Journal of gastroenterology · 2015Guideline
- Improvement of dyspeptic symptoms afterJGH open : an open access journal of gastroenterology and hepatology · 2023Article
- A Malaysian consensus report on the diagnosis and treatment ofJGH open : an open access journal of gastroenterology and hepatology · 2023Review
- The Usefulness of Symptom-based Subtypes of Functional Dyspepsia for Predicting Underlying Pathophysiologic Mechanisms and Choosing Appropriate Therapeutic Agents.Journal of neurogastroenterology and motility · 2021Review
- Helicobacter pylori infection progresses proximally associated with pyloric metaplasia in age-dependent tendency: a cross-sectional study.BMC gastroenterology · 2018Article
- Helicobacter pylori: Helicobacter pylori gastritis--a novel distinct disease entity.Nature reviews. Gastroenterology & hepatology · 2015Article
- Association of the Extent of Atrophic Gastritis With Specific Dyspeptic Symptoms.Journal of neurogastroenterology and motility · 2015Article
- Review
- Eosinophils and mast cells as therapeutic targets in pediatric functional dyspepsia.World journal of gastrointestinal pharmacology and therapeutics · 2013Review
- Role of Helicobacter pylori in Functional Dyspepsia: More Controversies Than Answers.Journal of neurogastroenterology and motility · 2013Article
- Effect of Helicobacter pylori Eradication on Functional Dyspepsia.Journal of neurogastroenterology and motility · 2013Article
- Helicobacter pylori infection in functional dyspepsia.Nature reviews. Gastroenterology & hepatology · 2013Review
- Why dyspepsia can occur without organic disease: pathogenesis and management of functional dyspepsia.Journal of gastroenterology · 2012Review
- Hellenic consensus onAnnals of gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional dyspepsia is a group of disorders featuring symptoms believed to be derived from the stomach and duodenum such as upper abdominal discomfort, pain, postprandial fullness and early satiety. A key diagnostic requisite is the absence of organic, metabolic, or systemic disorders to explain "dyspeptic symptoms." Therefore, when peptic ulcer diseases (including scars), erosive esophagitis and upper gastrointestinal malignancies are found at endoscopic examinations, the diagnosis of functional dyspepsia is excluded. One notable exception, however, is Helicobacter pylori infection. According to the Rome III definition, H. pylori infection is included in functional dyspepsia. This is an obvious deviation from the diagnostic principle of functional dyspepsia, since H. pylori infection is a definite cause of mucosal inflammation, which affects a number of important gastric physiologies such as acid secretion, gastric endocrine function and motility. The chronic persistent nature of infection also results in more dramatic mucosal changes such as atrophy or intestinal metaplasia, the presence of which in the esophagus (Barrett's esophagus) precludes the diagnosis of functional dyspepsia. Since careful endoscopic examination can diagnose reliably H. pylori infection not only in Japan but also in Western contries, it is now feasible and more logical to exclude patients with chronic gastritis caused by H. pylori infection as having dyspeptic symptoms. It is time to establish the Asian consensus to declare that H. pylori infection should be separated from functional dyspepsia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.