Evidence mapPaperPMID 22192273Full record

Trial reportTrials2011

A practice-based trial of blood pressure control in African Americans (TLC-Clinic): study protocol for a randomized controlled trial.

Antoinette Schoenthaler, Leanne Luerassi, Jeanne A Teresi, Stephanie Silver, Jian Kong, Taiye Odedosu, Samantha Trilling, Anna Errico, Oshevire Uvwo, Kimberly Sebek and 2 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01070056 (Practice-based Trial of Blood Pressure Control in African Americans), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01070056 phase3completednot on this map

Practice-based Trial of Blood Pressure Control in African Americans

TypeinterventionalSponsorNYU Langone HealthRan2010 to 2012Enrolled194ConditionsHypertension, Physical Activity, Diet, Medication AdherenceArmsTherapeutic Lifestyle Changes (MINT-TLC), Usual Care
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Antoinette SchoenthalerCenter for Healthful Behavior Change, New York University School of Medicine, Department of Medicine, Division of General Internal Medicine, New York, NY, USA. Antoinette.Schoenthaler@nyumc.org
Leanne Luerassi
Jeanne A Teresi
Stephanie Silver
Jian Kong
Taiye Odedosu
Samantha Trilling
Anna Errico
Oshevire Uvwo
Kimberly Sebek
Adetutu Adekoya
Gbenga Ogedegbe
New York University · USHebrew Home · USBellevue Hospital Center · USNew York Psychoanalytic Society and Institute · US

Funding

NCRR NIH HHS 1UL1RR029893-0109NHLBI NIH HHS R01 HL087301-01A2
6 · The paper itself

Abstract

backgroundPoorly controlled hypertension (HTN) remains one of the most significant public health problems in the United States, in terms of morbidity, mortality, and economic burden. Despite compelling evidence supporting the beneficial effects of therapeutic lifestyle changes (TLC) for blood pressure (BP) reduction, the effectiveness of these approaches in primary care practices remains untested, especially among African Americans, who share a disproportionately greater burden of HTN-related outcomes. METHODS/

designThis randomized controlled trial tests the effectiveness of a practice-based comprehensive therapeutic lifestyle intervention, delivered through group-based counseling and motivational interviewing (MINT-TLC) versus Usual Care (UC) in 200 low-income, African Americans with uncontrolled hypertension. MINT-TLC is designed to help patients make appropriate lifestyle changes and develop skills to maintain these changes long-term. Patients in the MINT-TLC group attend 10 weekly group classes focused on healthy lifestyle changes (intensive phase); followed by 3 monthly individual motivational interviewing (MINT) sessions (maintenance phase). The intervention is delivered by trained research personnel with appropriate treatment fidelity procedures. Patients in the UC condition receive a single individual counseling session on healthy lifestyle changes and print versions of the intervention materials. The primary outcome is within-patient change in both systolic and diastolic BP from baseline to 6 months. In addition to BP control at 6 months, other secondary outcomes include changes in the following lifestyle behaviors from baseline to 6 months: a) physical activity, b) weight loss, c) number of daily servings of fruits and vegetables and d) 24-hour urinary sodium excretion. DISCUSSION: This vanguard trial will provide information on how to refine MINT-TLC and integrate it into a standard treatment protocol for hypertensive African Americans as a result of the data obtained; thus maximizing the likelihood of its translation into clinical practice.

trial registrationClinicaltrials.gov NCT01070056.

Indexed as

Clinical ProtocolsBlack or African AmericanCounselingHumansHypertensionInterviews as TopicLife StyleMotivationSample SizeTreatment Outcome

Identifiers

PMID22192273
PMCPMC3264527
OpenAlexW2150134535

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.