Evidence map›Paper›PMID 22207679›Full record

ArticleChest2012

The impact of COPD on management and outcomes of patients hospitalized with acute myocardial infarction: a 10-year retrospective observational study.

Mihaela S Stefan, Raveendhara R Bannuru, Darleen Lessard, Joel M Gore, Peter K Lindenauer, Robert J Goldberg

Open access · bronzeAbstract read
In one paragraph

Article in Chest, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Diagnosis and management of comorbid disease in COPD.Breathe (Sheffield, England) · 2025
    Review
  4. Article
  5. Article
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  9. Article
  10. Article
  11. Article
  12. COPD and acute myocardial infarction.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  13. Article
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  17. Article
  18. Review
  19. Review
  20. Effectiveness and safety of concurrent beta-blockers and inhaled bronchodilators in COPD with cardiovascular comorbidities.European respiratory review : an official journal of the European Respiratory Society · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mihaela S StefanDepartment of General Medicine, Baystate Medical Center, Springfield, MA; Tufts Clinical and Translational Science Institute, Tufts University School of Medicine, Boston, MA. Electronic address: mihaela.stefan@bhs.org.
Raveendhara R BannuruTufts Clinical and Translational Science Institute, Tufts University School of Medicine, Boston, MA.
Darleen LessardDepartment of Quantitative Health Sciences, Worcester, MA; University of Massachusetts Medical School, Worcester, MA.
Joel M GoreDepartment of Medicine, Worcester, MA; University of Massachusetts Medical School, Worcester, MA.
Peter K LindenauerDepartment of General Medicine, Baystate Medical Center, Springfield, MA; Tufts Clinical and Translational Science Institute, Tufts University School of Medicine, Boston, MA.
Robert J GoldbergDepartment of Quantitative Health Sciences, Worcester, MA; University of Massachusetts Medical School, Worcester, MA.
University of Massachusetts Chan Medical School · USTufts University · USBaystate Medical Center · US

Funding

TUFTS CLINICAL AND TRANSLATION SCIENCE INSTITUTE (UL1): BPCAUL1RR025752 · NCRR · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2008 to 2011
$17.6M
WORCHESTER HEART ATTACK COMMUNITY SURVEILLANCE STUDYR01HL035434 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GOLDBERG, ROBERT JOEL · 1987 to 2014
$7.4M
POSTDOCTORAL FELLOWSHIPS IN HEALTH SERVICES RESEARCHT32HS000060 · AHRQ · TUFTS MEDICAL CENTER · PI SELKER, HARRY P. · 1993 to 2012
$2.9M
Tufts CTSI Career Development Program in Comparative Effectiveness ResearchKM1CA156726 · NCI · TUFTS UNIVERSITY BOSTON · PI KENT, DAVID M, SELKER, HARRY P. · 2010 to 2010
$2.5M
AHRQ HHS T32 HS000060NCI NIH HHS KM1 CA156726NCRR NIH HHS UL1 RR025752NHLBI NIH HHS R01 HL035434NHLBI NIH HHS R01 HL35434
6 · The paper itself

Abstract

backgroundThere are limited data describing contemporary trends in the management and outcomes of patients with COPD who develop acute myocardial infarction (AMI).

methodsThe study population consisted of patients hospitalized with AMI at all greater Worcester, Massachusetts, medical centers between 1997 and 2007.

resultsOf the 6,290 patients hospitalized with AMI, 17% had a history of COPD. Patients with COPD were less likely to be treated with β-blockers or lipid-lowering therapy or to have undergone interventional procedures during their index hospitalization than patients without COPD. Patients with COPD were at higher risk for dying during hospitalization (13.5% vs 10.1%) and at 30 days after discharge (18.7% vs 13.2%), and their outcomes did not improve during the decade-long period under study. After multivariable adjustment, the adverse effects of COPD remained on both in-hospital (OR, 1.25; 95% CI, 0.99-1.50) and 30-day all-cause mortality (OR, 1.31; 95% CI, 1.10-1.58). The use of evidence-based therapies for all patients with AMI increased between 1997 and 2007, with a particularly marked increase for patients with COPD.

conclusionsOur results suggest that the gap in medical care between patients with and without COPD hospitalized with AMI narrowed substantially between 1997 and 2007. Patients with COPD, however, remain less aggressively treated and are at increased risk for hospital adverse outcomes than patients without COPD in the setting of AMI. Careful consideration is necessary to ensure that these high-risk complex patients are not denied the benefits of effective cardiac therapies.

Indexed as

AgedChi-Square DistributionFemaleHospitalizationHumansIncidenceMaleMassachusettsMyocardial InfarctionOutcome Assessment, Health CarePulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsTreatment Outcome

Identifiers

PMID22207679
PMCPMC3367486
OpenAlexW2105093119

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.