ArticleCryobiology2012
Persufflation (or gaseous oxygen perfusion) as a method of organ preservation.
Article in Cryobiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Pooled it
- Clinical Evolution, Outcomes, and Emerging Preservation Technologies in Pancreas and Islet Transplantation.Journal of clinical medicine · 2026Review
- Use of Antegrade Coronary Oxygen Persufflation as a Strategy for Donor Heart Preservation.Brazilian journal of cardiovascular surgery · 2025Article
- Biostasis: A Roadmap for Research in Preservation and Potential Revival of Humans.Brain sciences · 2024Review
- Antegrade persufflation of porcine kidneys improves renal function after warm ischemia.Frontiers in transplantation · 2024Article
- Study of Hepatic Vascular Dynamics Based on Symmetrical Pulsating Perfusion.Annals of transplantation · 2019Article
- Oxygen Perfusion (Persufflation) of Human Pancreata Enhances Insulin Secretion and Attenuates Islet Proinflammatory Signaling.Transplantation · 2019Article
- Subunit composition of respiratory chain complex 1 and its responses to oxygen in mitochondria from human donor livers.BMC research notes · 2017Article
- Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement.Transplantation · 2016Article
- Continuous Quadrupole Magnetic Separation of Islets during Digestion Improves Purified Porcine Islet Viability.Journal of diabetes research · 2016Article
- Cryoprotectant Toxicity: Facts, Issues, and Questions.Rejuvenation research · 2015Review
- Short- and long-term outcomes of kidney transplants with kidneys lavaged by retrograde perfusion technique.Chronic diseases and translational medicine · 2015Article
- Perfusion machines for liver transplantation: technology and multifunctionality.Updates in surgery · 2014Review
- Maintenance of ischemic β cell viability through delivery of lipids and ATP by targeted liposomes.Biomaterials science · 2014Article
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
Improved preservation techniques have the potential to improve transplant outcomes by better maintaining donor organ quality and by making more organs available for allotransplantation. Persufflation, (PSF, gaseous oxygen perfusion) is potentially one such technique that has been studied for over a century in a variety of tissues, but has yet to gain wide acceptance for a number of reasons. A principal barrier is the perception that ex vivo PSF will cause in vivo embolization post-transplant. This review summarizes the extensive published work on heart, liver, kidney, small intestine and pancreas PSF, discusses the differences between anterograde and retrograde PSF, and between PSF and other conventional methods of organ preservation (static cold storage, hypothermic machine perfusion). Prospective implications of PSF within the broader field of organ transplantation, and in the specific application with pancreatic islet isolation and transplant are also discussed. Finally, key issues that need to be addressed before PSF becomes a more widely utilized preservation strategy are summarized and discussed.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.