ReviewComparative medicine2011
Obesity in rhesus and cynomolgus macaques: a comparative review of the condition and its implications for research.
Review in Comparative medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 76 citations in OpenAlex.
- The Influence of Genetic Background and Housing Conditions on Spontaneous Obesity in Captive-Bred Rhesus Monkeys (Macaca mulatta).Journal of medical primatology · 2026Article
- Association of Primate Veterinarians Guidelines for Weight Management in Research Nonhuman Primates.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.PLoS pathogens · 2025Article
- Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates.JCI insight · 2024Article
- Evaluating enrichment use in group-housed rhesus macaques (Animal welfare (South Mimms, England) · 2024Article
- Impact of Dietary Regime and Seasonality on Hindgut's Mycobiota Diversity in Dairy Cows.Microorganisms · 2023Article
- Advancing methods for the biodemography of aging within social contexts.Neuroscience and biobehavioral reviews · 2023Review
- Bacterial Contamination of the Surgical Site at the Time of Elective Caesarean Section in Belgian Blue Cows-Part 2: Identified by 16Sr DNA Amplicon Sequencing.Veterinary sciences · 2023Article
- Effects of Elevated Maternal Adiposity on Offspring Reproductive Health: A Perspective From Epidemiologic Studies.Journal of the Endocrine Society · 2022Review
- Overweight Management through Mild Caloric Restriction in Multigenerational Long-Tailed Macaque Breeding Groups.Veterinary sciences · 2022Article
- Naturally Occurring Endocrine Disorders in Non-Human Primates: A Comprehensive Review.Animals : an open access journal from MDPI · 2022Review
- First Descriptive Analysis of the Faecal Microbiota of Wild and Anthropized Barbary Macaques (Biology · 2022Article
- Effect of Housing Conditions on Cortisol and Body Fat Levels in Female Rhesus Macaques.Biology · 2021Article
- Review
- Anti-obesity effects ofCanadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2021Article
- Diet, psychosocial stress, and Alzheimer's disease-related neuroanatomy in female nonhuman primates.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021Article
- Fecal Bacterial Microbiota of Healthy Free-Ranging, Healthy Corralled, and Chronic Diarrheic Corralled Rhesus Macaques (Comparative medicine · 2021Article
- Effect of Chronic Western Diets on Non-Alcoholic Fatty Liver of Male Mice Modifying the PPAR-γ Pathway via miR-27b-5p Regulation.International journal of molecular sciences · 2021Article
- Multi-Omics Comparison of the Spontaneous Diabetes Mellitus and Diet-Induced Prediabetic Macaque Models.Frontiers in pharmacology · 2021Article
- Large Lemurs: Ecological, Demographic and Environmental Risk Factors for Weight Gain in Captivity.Animals : an open access journal from MDPI · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is an increasingly important health issue in both humans and animals and has been highly correlated as a risk factor for hyperglycemic conditions in humans. Naturally occurring obesity has been extensively studied in nonhuman primates with a focus on the development of biomarkers for characterizing overweight individuals and tracking the progression of obesity to conditions such as type 2 diabetes mellitus. Animal models have provided a basic understanding of metabolism and carbohydrate physiology, and continue to contribute to ongoing research of obesity and its adverse health effects. This review focuses on spontaneous obesity in rhesus and cynomolgus macaques as a model for human obesity and type 2 diabetes mellitus, including associated risk factors for the development of obesity and obesity-related health conditions. Little is known about preventive measures to minimize obesity while maintaining a healthy colony of macaques, and numerous complexities such as social status, feeding behaviors, timing of feeding, food distribution, and stress have been identified as contributing factors to overweight body condition in both single and group housed nonhuman primates. As in humans, increased body weight and obesity in macaques affect their overall health status. These conditions may interfere with the suitability of some animals in various studies unrelated to obesity.
Indexed as
Identifiers
22330579PMC3236694W118110054What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.