Evidence mapPaperPMID 22355024Full record

ArticleDiabetes care2012

Metformin-induced hepatotoxicity.

Francisco Miralles-Linares, Susana Puerta-Fernandez, M Rosa Bernal-Lopez, Francisco J Tinahones, Raul J Andrade, Ricardo Gomez-Huelgas

Open access · hybridAbstract readCase ReportsLetter
In one paragraph

Article in Diabetes care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 54 citations in OpenAlex.

  1. Frontiers in pharmacology · 2025
    Review
  2. Article
  3. Exploring the Biological Effects of Anti-Diabetic Vanadium Compounds in the Liver, Heart and Brain.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. The Hormetic Effect of Metformin: "Less Is More"?International journal of molecular sciences · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. MechanisticPharmacognosy magazine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Francisco Miralles-Linares
Susana Puerta-Fernandez
M Rosa Bernal-Lopez
Francisco J Tinahones
Raul J Andrade
Ricardo Gomez-Huelgas
Hospital Clínico Universitario Virgen de la Victoria · ESHospital Doctor José Molina Orosa · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 2HumansHypoglycemic AgentsLiverMaleMetforminMiddle AgedHypoglycemic AgentsMetformin

Identifiers

PMID22355024
PMCPMC3322705
OpenAlexW2048381231

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.