Evidence map›Paper›PMID 22413089›Full record

ArticleG3 (Bethesda, Md.)2012

Production of a natural antibody to the mouse polyoma virus is a multigenic trait.

Erik Andrews, Palanivel Velupillai, Chang Kyoo Sung, David R Beier, Thomas Benjamin

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Erik Andrews
Palanivel Velupillai
Chang Kyoo Sung
David R Beier
Thomas Benjamin
Harvard University · US

Funding

POLYOMA HOST INTERACTIONS LEADING TO TUMOR DEVELOPMENTR01CA090992 · NCI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI BENJAMIN, THOMAS LIVINGSTON · 2001 to 2005
$3.7M
NCI NIH HHS R01 CA090992
6 · The paper itself

Abstract

MA/MyJ mice express a natural antibody to the highly oncogenic polyoma virus. C57BR/cdJ mice lack this antibody but mount an adaptive T-cell response to the virus. Analysis of F2 progeny of a cross between these strains reveals a pattern of inheritance of expression of the natural antibody involving two genes in an epistatic relationship.

Indexed as

epistasismultigenic inheritancenatural antibodypolyoma virus

Identifiers

PMID22413089
PMCPMC3291505
OpenAlexW2107957459

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.