ArticleEuropean journal of applied physiology2012
Dynamic response characteristics of hyperaemia in the human calf muscle: effect of exercise intensity and relation to electromyographic activity.
Article in European journal of applied physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Intensity-dependent effect of ageing on fatigue during intermittent contractions of the human calf muscle in males and females.European journal of applied physiology · 2015Trial
- The Role of Central Command in the Increase in Muscle Sympathetic Nerve Activity to Contracting Muscle During High Intensity Isometric Exercise.Frontiers in neuroscience · 2021Article
- Skeletal muscle microvascular perfusion responses to cuff occlusion and submaximal exercise assessed by contrast-enhanced ultrasound: The effect of age.Physiological reports · 2020Article
- Effect of obesity on oxygen uptake and cardiovascular dynamics during whole-body and leg exercise in adult males and females.Physiological reports · 2018Article
- The metaboreflex does not contribute to the increase in muscle sympathetic nerve activity to contracting muscle during static exercise in humans.The Journal of physiology · 2018Article
- Venous occlusion plethysmography vs. Doppler ultrasound in the assessment of leg blood flow kinetics during different intensities of calf exercise.European journal of applied physiology · 2018Article
- Contributions of Central Command and Muscle Feedback to Sympathetic Nerve Activity in Contracting Human Skeletal Muscle.Frontiers in physiology · 2016Article
- Interactive effect of acute sympathetic activation and exercise intensity on the dynamic response characteristics of vascular conductance in the human calf muscle.European journal of applied physiology · 2015Article
- Cardiovascular control during exercise in type 2 diabetes mellitus.Journal of diabetes research · 2015Review
- Assessment of calf muscle fatigue during submaximal exercise using transcranial magnetic stimulation versus transcutaneous motor nerve stimulation.European journal of applied physiology · 2014Article
- Effect of contraction intensity on sympathetic nerve activity to active human skeletal muscle.Frontiers in physiology · 2014Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To clarify the structure of the muscle hyperaemic response during submaximal exercise in the supine position, we tested the hypotheses that this response measured in human calf muscle is biphasic or triphasic (growth-only) at low-moderate or high forces, respectively. Ten subjects performed four series of 5-min bout of intermittent contractions from a resting baseline to 30, 60 and 90% of peak force, as well as from an exercise baseline to higher forces. For each exercise transition, leg blood flow (LBF: plethysmography) and leg vascular conductance (LVC) were measured between contractions and averaged across four trials. Six 'growth-only' and 'growth and decay' models were fitted to these averaged responses and significant differences between their goodness-of-fit were tested statistically. For rest-exercise transitions, triphasic or quadphasic 'growth and decay' models provided the best fit to the majority of LBF and LVC responses. The intensity-dependent growth in hyperaemia was due mainly to a significant increase in amplitude of the rapid growth phase. A fast decay in LBF and LVC occurred at all intensities (mean τ = 4-5 s, mean TD = 9-14 s). A slower decay appeared at the lowest intensity (mean τ = 18-28 s, TD ≅ 90 s) that coincided with a monoexponential decline in EMG activity (mean τ = 23, TD = 87 s). Thus, although biphasic growth is an essential feature of muscle hyperaemia, rapid and slow decay phases also exist that highlight additional mechanisms which contribute to this dynamic response during exercise.
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