Trial reportPloS one2012
A risk score to predict type 2 diabetes mellitus in an elderly Spanish Mediterranean population at high cardiovascular risk.
Trial report in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- MiRNAs as biomarkers of nutritional therapy to achieve T2DM remission in patients with coronary heart disease: from the CORDIOPREV study.Nutrition & diabetes · 2025Trial
- Development of a risk prediction score and equation for chronic kidney disease: a retrospective cohort study.Scientific reports · 2023Trial
- Assessing Type 2 Diabetes Risk in the Post-Pandemic Era: A Pharmacy-Led FINDRISC Screening Study.Life (Basel, Switzerland) · 2024Article
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- Performance of a Finnish Diabetes Risk Score in detecting undiagnosed diabetes among Kenyans aged 18-69 years.PloS one · 2023Article
- Understanding the risk of developing weight-related complications associated with different body mass index categories: a systematic review.Diabetology & metabolic syndrome · 2022Review
- Development of Various Diabetes Prediction Models Using Machine Learning Techniques.Diabetes & metabolism journal · 2022Article
- Development of a risk prediction score for hypertension incidence using Japanese health checkup data.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Identification of Risk Factors for Daptomycin-Associated Creatine Phosphokinase Elevation and Development of a Risk Prediction Model for Incidence Probability.Open forum infectious diseases · 2021Article
- Diagnostic validity of the pre-diabetes scale among at-risk rural Iranian adults for screening for pre-diabetes.Journal of diabetes and metabolic disorders · 2020Article
- Agreement between Type 2 Diabetes Risk Scales in a Caucasian Population: A Systematic Review and Report.Journal of clinical medicine · 2020Article
- Prognostic Modeling and Prevention of Diabetes Using Machine Learning Technique.Scientific reports · 2019Article
- Driving Type 2 Diabetes Risk Scores into Clinical Practice: Performance Analysis in Hospital Settings.Journal of clinical medicine · 2019Article
- Integration of Distributed Services and Hybrid Models Based on Process Choreography to Predict and Detect Type 2 Diabetes.Sensors (Basel, Switzerland) · 2017Article
- Development and Validation of a Risk-Score Model for Type 2 Diabetes: A Cohort Study of a Rural Adult Chinese Population.PloS one · 2016Article
- H2RM: A Hybrid Rough Set Reasoning Model for Prediction and Management of Diabetes Mellitus.Sensors (Basel, Switzerland) · 2015Article
- Article
- Analysis of a sample of type 2 diabetic patients with obesity or overweight and at cardiovascular risk: a cross sectional study in Spain.BMC research notes · 2014Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo develop and test a diabetes risk score to predict incident diabetes in an elderly Spanish Mediterranean population at high cardiovascular risk. MATERIALS AND
methodsA diabetes risk score was derived from a subset of 1381 nondiabetic individuals from three centres of the PREDIMED study (derivation sample). Multivariate Cox regression model ß-coefficients were used to weigh each risk factor. PREDIMED-personal Score included body-mass-index, smoking status, family history of type 2 diabetes, alcohol consumption and hypertension as categorical variables; PREDIMED-clinical Score included also high blood glucose. We tested the predictive capability of these scores in the DE-PLAN-CAT cohort (validation sample). The discrimination of Finnish Diabetes Risk Score (FINDRISC), German Diabetes Risk Score (GDRS) and our scores was assessed with the area under curve (AUC).
resultsThe PREDIMED-clinical Score varied from 0 to 14 points. In the subset of the PREDIMED study, 155 individuals developed diabetes during the 4.75-years follow-up. The PREDIMED-clinical score at a cutoff of ≥6 had sensitivity of 72.2%, and specificity of 72.5%, whereas AUC was 0.78. The AUC of the PREDIMED-clinical Score was 0.66 in the validation sample (sensitivity = 85.4%; specificity = 26.6%), and was significantly higher than the FINDRISC and the GDRS in both the derivation and validation samples. DISCUSSION: We identified classical risk factors for diabetes and developed the PREDIMED-clinical Score to determine those individuals at high risk of developing diabetes in elderly individuals at high cardiovascular risk. The predictive capability of the PREDIMED-clinical Score was significantly higher than the FINDRISC and GDRS, and also used fewer items in the questionnaire.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.