Evidence map›Paper›PMID 22461375›Full record

Trial reportPediatric obesity2012

Cardiovascular risk factors in multi-ethnic middle school students: the HEALTHY primary prevention trial.

S M Willi, K Hirst, R Jago, J Buse, F Kaufman, L El Ghormli, S Bassin, D Elliot, D E Hale, HEALTHY Study Group

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Pediatric obesity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 8 pooled it
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 8 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Interventions for preventing obesity in children.The Cochrane database of systematic reviews · 2019
    Pooled it
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  8. EFFECTIVENESS OF OBESITY INTERVENTION PROGRAMS BASED ON GUIDELINES FOR ADOLESCENT STUDENTS: SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo
    Pooled it
  9. Trial
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. The Report Card on BMI Report Cards.Current obesity reports · 2017
    Review
  16. Review
  17. Review
  18. Childhood obesity, arterial stiffness, and prevalence and treatment of hypertension.Current treatment options in cardiovascular medicine · 2014
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

S M WilliDeparment of Endocrinology/Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
K Hirst
R Jago
J Buse
F Kaufman
L El Ghormli
S Bassin
D Elliot
D E Hale
HEALTHY Study Group
George Washington University · USChildren's Hospital of Philadelphia · USOregon Health & Science University · USThe University of Texas Health Science Center at San Antonio · USUniversity of Bristol · GBUniversity of California, Irvine · USUniversity of North Carolina at Chapel Hill · USUniversity of Southern California · US

Funding

Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) StudyU01DK061230 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI BRAFFETT, BARBARA HALINA, ZEITLER, PHILIP S. · 2001 to 2019
$231.8M
Physical Activity in Youth-Preventing Type 2 DiabetesU01DK061223 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRELL, JOANNE S · 2002 to 2008
$13.1M
Exercise Strategy to Prevent Pediatric Type 2 DiabetesU01DK061249 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M · 2002 to 2008
$12.4M
Middle School Prevention of Type 2 DiabetesU01DK061231 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI BARANOWSKI, TOM · 2002 to 2008
$9.4M
NIDDK NIH HHS U01 DK061223NIDDK NIH HHS U01 DK061230NIDDK NIH HHS U01 DK061231NIDDK NIH HHS U01 DK061249NIDDK NIH HHS U01-DK61223NIDDK NIH HHS U01-DK61230NIDDK NIH HHS U01-DK61231NIDDK NIH HHS U01-DK61249
6 · The paper itself

Abstract

objectiveThe objective of this study was to examine the effects of an integrated, multi-component, school-based intervention programme on cardiovascular disease (CVD) risk factors among a multi-ethnic cohort of middle school students.

methodsHEALTHY was a cluster randomized, controlled, primary prevention trial. Middle school was the unit of randomization and intervention. Half of the schools were assigned to an intervention programme consisting of changes in the total school food environment and physical education classes, enhanced by educational outreach and behaviour change activities and promoted by a social marketing campaign consisting of reinforcing messages and images. Outcome data reported (anthropometrics, blood pressure and fasting lipid levels) were collected on a cohort of students enrolled at the start of 6th grade (∼11-12 years old) and followed to end of 8th grade (∼13-14 years old).

resultsForty-two middle schools were enrolled at seven field centres; 4363 students provided both informed consent and CVD data at baseline and end of study. The sample was 52.7% female, 54.5% Hispanic, 17.6% non-Hispanic Black, 19.4% non-Hispanic White and 8.5% other racial/ethnic combinations, and 49.6% were categorized as overweight or obese (body mass index ≥ 85th percentile) at baseline. A significant intervention effect was detected in the prevalence of hypertension in non-Hispanic Black and White males. The intervention produced no significant changes in lipid levels.

conclusionsThe prevalence of some CVD risk factors is high in minority middle school youth, particularly males. A multi-component, school-based programme achieved only modest reductions in these risk factors; however, promising findings occurred in non-Hispanic Black and White males with hypertension.

Indexed as

EthnicityPreventive Health ServicesRisk Reduction BehaviorSchool Health ServicesAdolescentAdolescent BehaviorAge FactorsBiomarkersBlack or African AmericanBlood PressureBody Mass IndexChildChild BehaviorDietExerciseFemaleBiomarkersLipids

Identifiers

PMID22461375
PMCPMC3348358
OpenAlexW1868629592

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.