Evidence mapPaperPMID 22673021Full record

ArticleAmerican journal of hypertension2012

Feasibility and reproducibility of noninvasive 24-h ambulatory aortic blood pressure monitoring with a brachial cuff-based oscillometric device.

Athanase D Protogerou, Antonis Argyris, Efthymia Nasothimiou, Dimitris Vrachatis, Theodoros G Papaioannou, Dimitris Tzamouranis, Jacques Blacher, Michel E Safar, Petros Sfikakis, George S Stergiou

2 registry-linked trialsOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in American journal of hypertension, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02887677 phase4terminatedstarted 2016, after this paper: background citation

A Study of the Effects of Dapagliflozin on Ambulatory Aortic Pressure, Arterial Stiffness and Urine Albumin Excretion in Patients With Type 2 Diabetes

Ran2016Enrolled85Registered outcomes9Posted comparisons0ConditionsDiabetes MellitusArmsdapagliflozin, Placebo
Open the trial in the graph
NCT03607747 unknown statusnot on this mapstarted 2018, after this paper: background citation

Longitudinal Change of Arterial Stiffness Indices in Relation to Ambulatory Aortic and Branchial Pressure in Long Term Peritoneal Dialysis Patients

TypeobservationalSponsorAristotle University Of ThessalonikiRan2018 to 2020Enrolled40ConditionsEnd Stage Renal Disease, Peritoneal Dialysis, Arterial Sclerosis
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 79 citations in OpenAlex.

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  6. 24-hour isolated aortic systolic hypertension phenotype and its association with carotid and cardiac damage: the SAFAR study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
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  8. Another step forward in the introduction of aortic systolic blood pressure assessment into clinical practice?Hypertension research : official journal of the Japanese Society of Hypertension · 2024
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  9. 24-h central pressure is a valuable predictor for left ventricular hypertrophy in non-dialysis patients with chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Athanase D ProtogerouHypertension Center and Cardiovascular Research Laboratory, 1st Department of Propaedeutic Medicine, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece. aprotog@med.uoa.gr
Antonis Argyris
Efthymia Nasothimiou
Dimitris Vrachatis
Theodoros G Papaioannou
Dimitris Tzamouranis
Jacques Blacher
Michel E Safar
Petros Sfikakis
George S Stergiou
National and Kapodistrian University of Athens · GRSotiria General Hospital · GRLaiko General Hospital of Athens · GRDélégation Paris 5 · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccumulating evidence suggests the potential superiority of office aortic blood pressure (BP) over brachial in the management of arterial hypertension. The noninvasive aortic 24-h ambulatory brachial BP monitoring (ABPM) is potentially the optimal method for assessing BP profile. The objective of the present study was to investigate the feasibility and reproducibility to perform noninvasively 24-h aortic ABPM with a novel validated brachial cuff-based automatic oscillometric device (Mobilo-O-Graph) which records brachial BP and waveforms and assesses aortic BP via mathematical transformation.

methodsThirty consecutive subjects (mean age: 53.6 ± 11.6 years, 17 men) had a test-retest ABPM with at least 1-week interval. No modification of vasoactive drug treatment during the interval was allowed while similar 24-h activity during both recording days was recommended.

resultsThe average number of valid readings for brachial vs. aortic BP were 69.9 ± 10.4 vs. 58.0 ± 13.3 in the initial 24-h assessment (P < 0.001) and 68.3 ± 10.8 vs. 56.4 ± 13.6 in the repeat assessment (P < 0.001). No differences in average 24 h aortic BP values were observed between the two assessments (systolic blood pressure (SBP) 115.9 ± 7.7 vs. 115.1 ± 6.0 mm Hg, respectively, P = 0.48, and diastolic 79.7 ± 7.4 vs. 79.2 ± 8.7, P = 0.54). Reproducibility indices of aortic pressure including, intraclass coefficient of variation (SBP: 0.80 (95% confidence interval 0.58-0.90); diastolic: 0.92 (0.83-0.96)) and s.d. of differences (SBP/diastolic: 6.0/4.5 mm Hg) indicated acceptable reproducibility. The Bland-Altman plots indicated no evidence of systemic bias.

conclusionsIn conclusion, these data suggest that noninvasive 24-h ABPM is feasible and provides reproducible values. Future studies should validate the prognostic ability of 24-h aortic hemodynamics.

Indexed as

AdultArterial PressureBlood PressureBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryBrachial ArteryFeasibility StudiesFemaleHumansMaleMiddle AgedOscillometryReproducibility of Results

Identifiers

PMID22673021
OpenAlexW2330723531

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.