ArticleThe Journal of pediatrics2012
Thermal imaging to assess age-related changes of skin temperature within the supraclavicular region co-locating with brown adipose tissue in healthy children.
Article in The Journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05419726 (Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.), which is not on this map. Cited by 58 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.
Who cites it
58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 154 citations in OpenAlex.
- Effects of mirabegron on brown adipose tissue and metabolism in humans: A systematic review and meta-analysis.European journal of clinical pharmacology · 2024Pooled it
- Skin Temperature of Acupoints in Health and Disease: A Systematic Review.Journal of integrative and complementary medicine · 2022Pooled it
- A systematic review on the role of infrared thermography in the Brown adipose tissue assessment.Reviews in endocrine & metabolic disorders · 2020Pooled it
- Infrared Thermography for Estimating Supraclavicular Skin Temperature and BAT Activity in Humans: A Systematic Review.Obesity (Silver Spring, Md.) · 2019Pooled it
- The Effects of Nitrate on Brown Fat Fraction and Activation in Older Adults With Type 2 Diabetes: A Randomised, Double-Blind and Placebo-Controlled Crossover Trial.European journal of sport science · 2026Trial
- Effect of Liothyronine Treatment on Dermal Temperature and Activation of Brown Adipose Tissue in Female Hypothyroid Patients: A Randomized Crossover Study.Frontiers in endocrinology · 2021Trial
- A new method of infrared thermography for quantification of brown adipose tissue activation in healthy adults (TACTICAL): a randomized trial.The journal of physiological sciences : JPS · 2017Trial
- Glucocorticoids modulate human brown adipose tissue thermogenesis in vivo.Metabolism: clinical and experimental · 2017Trial
- Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation.Cell metabolism · 2016Trial
- Supraclavicular skin temperature as a measure of 18F-FDG uptake by BAT in human subjects.PloS one · 2014Trial
- Thermographic Quantification of Skin Prick Test Responses in Children: The Caloric Allergy Index: Thermographic Analysis: Pediatric Skin Prick Tests.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026Observational
- Investigation of the relationship between BAT activity and thermal comfort under short-term cold temperature exposure.Scientific reports · 2025Article
- Infrared thermography unveiled the variation of brown adipose tissue thermogenesis among East Asian adults.Physiological reports · 2025Article
- Genetic evidence for involvement of β2-adrenergic receptor in brown adipose tissue thermogenesis in humans.International journal of obesity (2005) · 2024Article
- Biomarkers of aging.Science China. Life sciences · 2023Review
- Both caffeine andFrontiers in physiology · 2022Article
- Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men.Cell reports. Medicine · 2021Article
- Semi-automated analysis of supraclavicular thermal images increases speed of brown adipose tissue analysis without increasing variation in results.Current research in physiology · 2021Article
- Use of Infrared Thermography to Estimate Brown Fat Activation After a Cooling Protocol in Patients with Severe Obesity That Underwent Bariatric Surgery.Obesity surgery · 2020Article
- Brown fat activity determined by infrared thermography and thermogenesis measurement using whole body calorimetry (BRIGHT Study).Physiological research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo establish the feasibility of infrared thermal imaging as a reproducible, noninvasive method for assessing changes in skin temperature within the supraclavicular region in vivo. STUDY
designThermal imaging was used to assess the effect of a standard cool challenge (by placement of the participant's feet or hand in water at 20°C) on the temperature of the supraclavicular region in healthy volunteer participants of normal body mass index in 3 age groups, 3-8, 13-18, and 35-58 years of age.
resultsWe demonstrated a highly localized increase in temperature within the supraclavicular region together with a significant age-related decline under both baseline and stimulated conditions.
conclusionThermogenesis within the supraclavicular region can be readily quantified by thermal imaging. This noninvasive imaging technique now has the potential to be used to assess brown adipose tissue function alone, or in combination with other techniques, in order to determine the roles of thermogenesis in energy balance and, therefore, obesity prevention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.