ArticleAnnals of epidemiology2012
Effects of cardiorespiratory fitness on aging: glucose trajectory in a cohort of healthy men.
Article in Annals of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Health and Functional Benefits of Eccentric versus Concentric Exercise Training: A Systematic Review and Meta-Analysis.Journal of sports science & medicine · 2023Pooled it
- Article
- Association of fasting plasma glucose trajectory with lifetime risk of cardiovascular disease.European journal of clinical nutrition · 2023Article
- Longitudinal Change in Fasting Blood Glucose and Myocardial Infarction Risk in a Population Without Diabetes.Diabetes care · 2017Article
- Longitudinal fasting blood glucose patterns and arterial stiffness risk in a population without diabetes.PloS one · 2017Article
- Sedentary Patterns, Physical Activity, and Cardiorespiratory Fitness in Association to Glycemic Control in Type 2 Diabetes Patients.Frontiers in physiology · 2017Article
- The effect of cardiorespiratory fitness on age-related lipids and lipoproteins.Journal of the American College of Cardiology · 2015Article
- Longitudinal trajectories of cholesterol from midlife through late life according to apolipoprotein E allele status.International journal of environmental research and public health · 2014Article
- Effects of cardiorespiratory fitness on blood pressure trajectory with aging in a cohort of healthy men.Journal of the American College of Cardiology · 2014Article
- Article
- Impact of Moderate Aerobic Training on Physical Capacities of Hypertensive Obese Elderly.Gerontology & geriatric medicineArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
purposeWe modeled the age-related trajectory of glucose and determined whether cardiorespiratory fitness altered the trajectory in a cohort of men from the Aerobics Center Longitudinal Study.
methodsA total of 10,092 men free of diagnosed diabetes, cardiovascular disease, and cancer, ages 20 to 90 years, completed from 2 to 21 health examinations between 1977 and 2005. Cardiorespiratory fitness was measured by a maximal treadmill exercise test and normalized for age. The covariates included waist circumference, hypertension, elevated cholesterol, smoking behavior, and physical activity.
resultsLinear mixed models regression analysis showed that fasting glucose increased at a linear rate with aging. Glucose increased at a yearly rate of 0.17 mg/dL (95% confidence interval: 0.16-0.19). Fitness had little influence on the aging glucose trajectory below age 35, but significantly influenced the trend after age 35 (P for interaction < .001). The aging-related glucose increases in low-fitness men (0.25 mg/dL per year) was greater than average-fitness (0.15 mg/dL per year) and high-fitness (0.13 mg/dL per year) men.
conclusionsThe aging-related fasting glucose increases in low-fitness men was nearly double that of high-fitness men. Our results may suggest that it is possible to delay the age-related glucose impairment through increasing one's fitness level.
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