Evidence map›Paper›PMID 22805289›Full record

ArticleCardiovascular diabetology2012

Glycosylated hemoglobin (HbA1c) levels and clinical outcomes in diabetic patients following coronary artery stenting.

Seyed Ebrahim Kassaian, Hamidreza Goodarzynejad, Mohammad Ali Boroumand, Mojtaba Salarifar, Farzad Masoudkabir, Mohammad Reza Mohajeri-Tehrani, Hamidreza Pourhoseini, Saeed Sadeghian, Narges Ramezanpour, Mohammad Alidoosti and 3 more

Abstract read
In one paragraph

Article in Cardiovascular diabetology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  14. Glycated Haemoglobin Levels and Its Effect on Outcomes in Cardiac Surgery.Brazilian journal of cardiovascular surgery · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Seyed Ebrahim KassaianDepartment of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Hamidreza Goodarzynejad
Mohammad Ali Boroumand
Mojtaba Salarifar
Farzad Masoudkabir
Mohammad Reza Mohajeri-Tehrani
Hamidreza Pourhoseini
Saeed Sadeghian
Narges Ramezanpour
Mohammad Alidoosti
Elham Hakki
Soheil Saadat
Ebrahim Nematipour

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes has been shown to be independent predictor of restenosis after percutaneous coronary intervention (PCI). The aim of the present study was to investigate whether a pre- and post-procedural glycaemic control in diabetic patients was related to major advance cardiovascular events (MACE) during follow up.

methodsWe evaluated 2884 consecutive patients including 2181 non-diabetic patients and 703 diabetics who underwent coronary stenting. Diabetes mellitus was defined as the fasting blood sugar concentration ≥ 126  mg/dL, or the use of an oral hypoglycemic agent or insulin at the time of admission. Diabetic patients were categorized into two groups based on their mean HbA1c levels for three measurements (at 0, 1, and 6  months following procedure): 291 (41.4%) diabetics with good glycaemic control (HbA1c ≤ 7%) and 412 (58.6%) diabetics with poor glycaemic control (HbA1c > 7%).

resultsThe adjusted risk of MACE in diabetic patients with poor glycaemic control (HbA1c > 7%) was 2.1 times of the risk in non-diabetics (adjusted HR = 2.1, 95% CI: 1.10 to 3.95, p = 0.02). However, the risk of MACE in diabetics with good glycaemic control (HbA1c ≤ 7%) was not significantly different from that of non-diabetics (adjusted HR = 1.33, 95% CI: 0.38 to 4.68, p = 0.66).

conclusionsOur data suggest that there is an association between good glycaemic control to obtain HbA1c levels ≤7% (both pre-procedural glycaemic control and post-procedural) with a better clinical outcome after PCI.

Indexed as

StentsAgedBiomarkersBlood GlucoseCardiovascular DiseasesChi-Square DistributionCoronary Artery DiseaseDiabetes MellitusDisease-Free SurvivalFemaleGlycated HemoglobinHumansHypoglycemic AgentsInsulinIranKaplan-Meier EstimateBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsInsulin

Identifiers

PMID22805289
PMCPMC3444922

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.