ReviewCurrent diabetes reports2012
Transplantation of the pancreas.
Review in Current diabetes reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Perfusion Computed Tomography for Assessing Pancreas Graft Volumetric Perfusion After Simultaneous Pancreas and Kidney Transplantation.Diagnostics (Basel, Switzerland) · 2024Article
- Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets.Scientific reports · 2021Article
- Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas.Scientific reports · 2018Article
- Exocrine drainage in vascularized pancreas transplantation in the new millennium.World journal of transplantation · 2016Review
- New Insights into Diabetes Cell Therapy.Current diabetes reports · 2016Review
- Imaging in pancreatic transplants.The Indian journal of radiology & imaging · 2014Article
- Transplant options for patients with type 2 diabetes and chronic kidney disease.World journal of transplantation · 2014Review
- Imaging pancreas transplants.The British journal of radiology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pancreas transplantation consistently induces insulin-independence in beta-cell-penic diabetic patients, but at the cost of major surgery and life-long immunosuppression. One year after grafting, patient survival rate now exceeds 95 % across recipient categories, while insulin independence is maintained in some 85 % of simultaneous pancreas and kidney recipients and in nearly 80 % of solitary pancreas transplant recipients. The half-life of the pancreas graft currently averages 16.7 years, being the longest among extrarenal grafts, and substantially matching the one of renal grafts from deceased donors. The difference between expected (100 %) and actual insulin-independence rate is mostly explained by technical failure in the postoperative phase, and rejection in the long-term period. Death with a functioning graft remains a further major issue, especially in uremic patients who have undergone prolonged periods of dialysis. Refinements in graft preservation, surgical techniques, immunosuppression, and prophylactic treatments are expected to further improve the results of pancreas transplantation.
Indexed as
Identifiers
22828824What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.