ArticleIndian journal of endocrinology and metabolism2012
Ileal interposition with sleeve gastrectomy for treatment of type 2 diabetes mellitus.
Article in Indian journal of endocrinology and metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Surgical cure for type 2 diabetes by foregut or hindgut operations: a myth or reality? A systematic review.Surgical endoscopy · 2017Pooled it
- The long-term effects of bariatric surgery for type 2 diabetes: systematic review and meta-analysis of randomized and non-randomized evidence.Obesity surgery · 2015Pooled it
- Outcomes of a Novel Surgery: Gastrojejunal-Ileal Interposition with Bipartition and Sleeve Gastrectomy for Type 2 Diabetes and Obesity.Journal of clinical medicine · 2026Article
- Long-term Effect of Ileal Transposition on Adipokine Serum Level in Zucker (Orl)-Lepr(fa) Fatty Rats.Obesity surgery · 2015Article
- Ileal interposition surgery for treatment of type 2 diabetes mellitus-pros and cons.Journal of diabetes and metabolic disorders · 2015Article
- Efficacy of metabolic surgery on HbA1c decrease in type 2 diabetes mellitus patients with BMI <35 kg/m2--a review.Obesity surgery · 2014Review
- Prediction of remission after metabolic surgery using a novel scoring system in type 2 diabetes - a retrospective cohort study.Journal of diabetes and metabolic disorders · 2014Article
- Glycemic variability: Clinical implications.Indian journal of endocrinology and metabolism · 2013Article
- Metabolic Surgery for Type 2 Diabetes in Patients with a BMI of <35 kg/m(2): A Surgeon's Perspective.Obesity surgery · 2013Review
- Ileal Interposition with Diverted sleeve gastrectomy for treatment of Type 2 diabetes.Indian journal of endocrinology and metabolism · 2012Article
- Bariatric surgery and diabetes remission: Who would have thought it?Indian journal of endocrinology and metabolismReview
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6 authors.
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Abstract
aimCombination of laparoscopic ileal interposition (II) with sleeve gastrectomy (SG) is an upcoming procedure, which offers good metabolic improvement and weight reduction without causing significant malabsorption. The objective of this study was to evaluate the results of this novel procedure for control of type 2 diabetes, obesity, hypertension, and related metabolic abnormalities. MATERIALS AND
methodsThe II and SG was performed in 43 patients (M:F = 25:18) from February 2008. Participants had a mean age of 47.2 ± 8.2 years (range 29-66 years), mean duration of diabetes of 10.1 ± 9.2 years (range 1-32 years), and mean preoperative body mass index (BMI) of 33.2 ± 7.8 kg/m2. All patients had poorly controlled type 2 diabetes mellitus (DM) [mean glycated hemoglobin (HbA1C) 9.6 ± 2.1%] despite use of oral hypoglycemic agents (OHAs) and/or insulin. Thirty (70%) patients had hypertension, 20 (46%) had dyslipidemia, and 18 (42%) had significant microalbuminuria. The primary outcome was remission of diabetes (HbA1C < 6.5% without OHAs/insulin) and the secondary outcomes were reduction in antidiabetic agent requirement and components of metabolic syndrome.
resultsMean follow-up was for 20.2 ± 8.6 months (range 4-40 months). Postoperatively, glycemic parameters (fasting and post-lunch blood sugar, HbA1C improved in all patients (P < 0.05) at all intervals. Twenty (47%) patients had remission in diabetes and the remaining patients showed significantly decreased OHA requirement. All patients had weight loss between 15 and 30% (P < 0.05). Twenty-seven (90%) patients had remission in hypertension. At 3 years, the mean fall in HbA1C (34%) was more than reduction in BMI (25%). There was a declining trend in lipids and microalbuminuria postoperatively, though it was significant for microalbuminuria only.
conclusionsThe laparoscopic II with SG seems to be a promising procedure for control of type 2 DM, hypertension, weight reduction, and associated metabolic abnormalities. A multicenter study with larger number of patients and a longer follow-up period is needed to substantiate our preliminary findings.
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