Evidence map›Paper›PMID 22854838›Full record

ReviewNature reviews. Cancer2012

The influence of race and ethnicity on the biology of cancer.

Brian E Henderson, Norman H Lee, Victoria Seewaldt, Hongbing Shen

Abstract readReview
In one paragraph

Review in Nature reviews. Cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Journal of racial and ethnic health disparities · 2026
    Article
  5. Shared genetic association between inflammatory bowel disease and acute myeloid leukemia: insights from mendelian randomization and transcriptomic analyses.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Association ofmedRxiv : the preprint server for health sciences · 2023
    Article
  14. Article
  15. Review
  16. Research Silos in Cancer Disparities: Obstacles to Improving Clinical Outcomes for Underserved Patient Populations.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brian E HendersonThe Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California 90033-0804, USA. behender@med.usc.edu
Norman H Lee
Victoria Seewaldt
Hongbing Shen

Funding

Multiethnic Cohort Study of Diet and CancerR37CA054281 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI KOLONEL, LAURENCE N. · 2003 to 2012
$23.2M
Transdisciplinary Research in Cancer of the Lung (TRICL)U19CA148127 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI AMOS, CHRISTOPHER I., LE MARCHAND, LOIC · 2010 to 2014
$10.9M
Epidemiological and Clinical Translational Studies Post Genome-Wide AssociationU19CA148537 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI EASTON, DOUGLAS FREDERICK, EELES, ROSALIND · 2010 to 2014
$10.4M
A Genome-wide Association Study of Prostate Cancer in African AmericansU01CA136792 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HENDERSON, BRIAN E · 2009 to 2011
$9.4M
MULTIETHNIC/MINORITY COHORT STUDY OF DIET AND CANCERR01CA054281 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI KOLONEL, LAURENCE N. · 1993 to 2002
$4.5M
Control of cAMP Mediated Glucagon Response by Bile AcidsR01DK056108 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI LEE, NORMAN H · 2001 to 2011
$2.7M
KCNK9 Imprinting in Breast Cancer Progression and MetastasisR01CA155664 · NCI · DUKE UNIVERSITY · PI SEEWALDT, VICTORIA L. · 2011 to 2015
$1.8M
Targeted Chemoprevention of Breast Cancer: From the Bench to Clinical TestingR01CA158668 · NCI · DUKE UNIVERSITY · PI SEEWALDT, VICTORIA L. · 2012 to 2016
$1.7M
Mapping Gene Networks in Colon CancerR01CA120316 · NCI · GEORGE WASHINGTON UNIVERSITY · PI LEE, NORMAN H · 2007 to 2010
$1.6M
Molecular markers of breast cancer risk and preventionR01CA114068 · NCI · DUKE UNIVERSITY · PI SEEWALDT, VICTORIA L. · 2006 to 2010
$1.3M
NCI NIH HHS CA054281NCI NIH HHS CA120316NCI NIH HHS CA136792NCI NIH HHS CA148537NCI NIH HHS R01 CA054281NCI NIH HHS R01 CA114068NCI NIH HHS R01 CA120316NCI NIH HHS R01 CA155664NCI NIH HHS R01 CA158668NCI NIH HHS R37 CA054281NCI NIH HHS U01 CA136792NCI NIH HHS U19 CA148127NCI NIH HHS U19 CA148537NIDDK NIH HHS DK056108NIDDK NIH HHS R01 DK056108
6 · The paper itself

Abstract

It is becoming clear that some of the differences in cancer risk, incidence and survival among people of different racial and ethnic backgrounds can be attributed to biological factors. However, identifying these factors and exploiting them to help eliminate cancer disparities has proved challenging. With this in mind, we asked four scientists for their opinions on the most crucial advances, as well as the challenges and what the future holds for this important emerging area of research.

Indexed as

GenomicsHumansIncidenceNeoplasmsRisk Factors

Identifiers

PMID22854838
PMCPMC3677949

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.