Evidence map›Paper›PMID 22914396›Full record

Trial reportObstetrics and gynecology2012

Predictors of success and satisfaction of nonsurgical therapy for stress urinary incontinence.

Joseph Schaffer, Charles W Nager, Fang Xiang, Diane Borello-France, Catherine S Bradley, Jennifer M Wu, Elizabeth Mueller, Peggy Norton, Marie Fidela R Paraiso, Halina Zyczynski and 1 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Obstetrics and gynecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Mechanical devices for urinary incontinence in women.The Cochrane database of systematic reviews · 2014
    Pooled it
  3. Trial
  4. Trial
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  8. Trial
  9. Article
  10. Article
  11. Observational
  12. Patient-Centered Goals for Treatment of Pelvic Floor Disorders.Current bladder dysfunction reports · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Joseph SchafferUniversity of Texas Southwestern, Dallas, TX, USA.
Charles W Nager
Fang Xiang
Diane Borello-France
Catherine S Bradley
Jennifer M Wu
Elizabeth Mueller
Peggy Norton
Marie Fidela R Paraiso
Halina Zyczynski
Holly E Richter
The University of Texas Southwestern Medical Center · US

Funding

Pelvic floor Disorders Network-Data Coordinating CenterU01HD041249 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEI, JOHN T · 2001 to 2010
$19.8M
Perioperative Pelvic Floor Rehab: A Rrandomized TrialU10HD041261 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RICHTER, HOLLY E · 2001 to 2015
$5.1M
UNC Pelvic Floor Disorders Research CollaborativeU10HD041267 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VISCO, ANTHONY G · 2001 to 2015
$5.0M
The Pelvic Floor Disorders NetworkU10HD041250 · NICHD · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA · 2001 to 2015
$3.8M
Pelvic Floor Disorders NetworkU10HD054214 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LUKACZ, EMILY S. · 2006 to 2015
$3.3M
The Cleveland Clinic Clinical SiteU10HD054215 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI BARBER, MATTHEW D · 2006 to 2015
$3.2M
Pittsburgh Collab Reconstructive Pelvic Surgery ProgramU10HD041263 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ZYCZYNSKI, HALINA M · 2001 to 2005
$2.3M
Treatment Investigation for Posterior ProlapseU10HD041268 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CUNDIFF, GEOFFREY WILLIAM · 2001 to 2005
$2.0M
Iowa Pelvic Floor Disorders Clinical Trials NetworkU10HD041248 · NICHD · UNIVERSITY OF IOWA · PI KREDER, KARL J · 2001 to 2005
$1.9M
NICHD Pelvic Floor Disorders Network Clinical Sites (U10)U10HD054241 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI SCHAFFER, JOSEPH I · 2006 to 2015
$1.9M
UTAH PELVIC FLOOR DISORDERS NETWORKU10HD054136 · NICHD · UNIVERSITY OF UTAH · PI NYGAARD, INGRID E · 2006 to 2015
$1.6M
Clinical Trials Network-Female Pelvic Floor DisordersU10HD041269 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI KIEBACK, DIRK · 2001 to 2003
$1.2M
NICHD NIH HHS U01 HD041249NICHD NIH HHS U01 HD41249NICHD NIH HHS U10 HD041248NICHD NIH HHS U10 HD041250NICHD NIH HHS U10 HD041261NICHD NIH HHS U10 HD041263NICHD NIH HHS U10 HD041267NICHD NIH HHS U10 HD041268NICHD NIH HHS U10 HD041269NICHD NIH HHS U10 HD054136NICHD NIH HHS U10 HD054214NICHD NIH HHS U10 HD054215NICHD NIH HHS U10 HD054241NICHD NIH HHS U10 HD41248NICHD NIH HHS U10 HD41250NICHD NIH HHS U10 HD41261NICHD NIH HHS U10 HD41263NICHD NIH HHS U10 HD41267NICHD NIH HHS U10 HD41268NICHD NIH HHS U10 HD41269NICHD NIH HHS U10 HD54136NICHD NIH HHS U10 HD54214NICHD NIH HHS U10 HD54215NICHD NIH HHS U10 HD54241
6 · The paper itself

Abstract

objectiveTo identify factors that may predict success and satisfaction in women undergoing nonsurgical therapy for stress urinary incontinence.

methodsBaseline demographic and clinical characteristics of women participating in a multicenter randomized trial of pessary, behavioral, or combined therapy for stress urinary incontinence were evaluated for potential predictors of success and satisfaction. Success and satisfaction outcomes were assessed at 3 months and included the Patient Global Impression of Improvement, stress incontinence subscale of the Pelvic Floor Distress Inventory, and Patient Satisfaction Questionnaire. Logistic regression was performed to identify predictors, adjusting for treatment and other important clinical covariates. Adjusted odds ratios (ORs), 95% confidence intervals (CIs), and associated P values are presented.

resultsFour hundred forty-six women were randomized. College education or more and no previous urinary incontinence surgery predicted success based on the stress subscale of the Pelvic Floor Distress Inventory (adjusted OR 1.61, 95% CI 1.01-2.55, P=.04 and adjusted OR 3.15, 95% CI 1.04- 9.53, P=.04, respectively). Menopausal status predicted success using the Patient Global Impression of Improvement (adjusted OR 2.52 postmenopausal compared with premenopausal, 95% CI 1.29-4.95; adjusted OR 1.32 unsure menopausal status compared with premenopausal, 95% CI 0.65-2.66; P=.03 across all three groups). Fewer than 14 incontinence episodes per week predicted satisfaction with the Patient Satisfaction Questionnaire (adjusted OR 1.97, 95% CI 1.21-3.19; P=.01). These predictors did not differ across the three treatment groups.

conclusionMenopause, higher education, no previous urinary incontinence surgery, and lower incontinence frequency were found to be predictors of success and satisfaction with nonsurgical therapy for stress urinary incontinence. This information may help better-align provider and patient expectations with nonsurgical treatment outcomes.

Indexed as

AdultAgedAged, 80 and overEducational StatusFemaleHumansMenopauseMiddle AgedPatient SatisfactionPessariesQuality of LifeSurveys and QuestionnairesTreatment OutcomeUrinary Incontinence, StressYoung Adult

Identifiers

PMID22914396
PMCPMC3427534
OpenAlexW2067836532

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.