Evidence mapPaperPMID 22929210Full record

ReviewInternational journal of obesity (2005)2013

Pharmacotherapy for childhood obesity: present and future prospects.

R Sherafat-Kazemzadeh, S Z Yanovski, J A Yanovski

Abstract readReview
In one paragraph

Review in International journal of obesity (2005), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2017 · on this map
    Guideline
  2. Drug interventions for the treatment of obesity in children and adolescents.The Cochrane database of systematic reviews · 2016
    Pooled it
  3. Article
  4. Review
  5. Review
  6. Pediatric Obesity Treatment: Considerations for Diabetes Educators and Clinicians.Diabetes spectrum : a publication of the American Diabetes Association · 2024
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Signaling pathways in obesity: mechanisms and therapeutic interventions.Signal transduction and targeted therapy · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Observational
  16. Pediatric Obesity, Hypertension, Lipids.Current treatment options in pediatrics · 2020
    Article
  17. Review
  18. Parental attitudes toward bariatric surgery in adolescents with obesity.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2020
    Article
  19. Article
  20. Effects of metformin in obesity treatment in different populations: a meta-analysis.Therapeutic advances in endocrinology and metabolism · 2020 · on this map
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

R Sherafat-KazemzadehSection on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1103, USA.
S Z Yanovski
J A Yanovski

Funding

Physiology, Psychology, and Genetics of ObesityZIAHD000641 · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · 2025 to 2025
$1.6M
Intramural NIH HHS Z99 DA999999Intramural NIH HHS Z99 HD999999Intramural NIH HHS Z99 HL999999Intramural NIH HHS Z99 MH999999Intramural NIH HHS Z99 OD999999Intramural NIH HHS ZIA HD000641
6 · The paper itself

Abstract

Pediatric obesity is a serious medical condition associated with significant comorbidities during childhood and adulthood. Lifestyle modifications are essential for treating children with obesity, yet many have insufficient response to improve health with behavioral approaches alone. This review summarizes the relatively sparse data on pharmacotherapy for pediatric obesity and presents information on obesity medications in development. Most previously studied medications demonstrated, at best, modest effects on body weight and obesity-related conditions. It is to be hoped that the future will bring new drugs targeting specific obesity phenotypes that will allow clinicians to use etiology-specific, and therefore more effective, anti-obesity therapies.

Indexed as

AdolescentAnti-Obesity AgentsAppetite DepressantsBody Mass IndexBrainChildDrug Therapy, CombinationEnergy MetabolismFemaleHumansInsulinIntestinal AbsorptionLipolysisMaleObesityOff-Label UseAnti-Obesity AgentsAppetite DepressantsInsulin

Identifiers

PMID22929210
PMCPMC3522799

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.