ReviewNature reviews. Endocrinology2012
Managing type 1 diabetes mellitus in pregnancy--from planning to breastfeeding.
Review in Nature reviews. Endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Stillbirth Among Patients With Diabetes in Pregnancy in Ethiopia: Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2021Pooled it
- Adverse birth outcome and associated factors among diabetic pregnant women in Ethiopia: Systematic review and meta-analysis.PloS one · 2020Pooled it
- Type 1 diabetes, diabetic nephropathy, and pregnancy: a systematic review and meta-study.The review of diabetic studies : RDS · 2013Pooled it
- Automated insulin delivery during the first 6 months postpartum (AiDAPT): a prespecified extension study.The lancet. Diabetes & endocrinology · 2025Trial
- The Lived Experiences of Adult Continuous Glucose Monitor Users with Type 1 Diabetes with Recurrent Severe Hypoglycemic Events and Impaired Awareness of Hypoglycemia: A Qualitative Study.Advances in therapy · 2026Article
- Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps.Epigenetics · 2022Review
- Flash glucose monitoring system in special situations.Archives of endocrinology and metabolism · 2022Review
- Dietary Advice to Support Glycaemic Control and Weight Management in Women with Type 1 Diabetes during Pregnancy and Breastfeeding.Nutrients · 2022Review
- Complex Management of Nephrotic Syndrome and Kidney Failure during Pregnancy in a Type 1 Diabetes Patient: A Challenging Case.Journal of clinical medicine · 2022Article
- Changes in Device Uptake and Glycemic Control Among Pregnant Women With Type 1 Diabetes: Data From the T1D Exchange.Journal of diabetes science and technology · 2021Article
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- Article
- The lived experiences of healthcare during pregnancy, birth, and three months after in women with type 1 diabetes mellitus.International journal of qualitative studies on health and well-being · 2020Article
- Maternal near miss and potentially life-threatening condition determinants in patients with type 1 diabetes mellitus at a university hospital in São Paulo, Brazil: a retrospective study.BMC pregnancy and childbirth · 2020Article
- Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus.Obstetrics and gynecology international · 2019Article
- Diabetes in pregnancy: a new decade of challenges ahead.Diabetologia · 2018Review
- Reprioritizing life: a conceptual model of how women with type 1 diabetes deal with main concerns in early motherhood.International journal of qualitative studies on health and well-being · 2017Article
- Women's Use of Health Care in the First 2 Years Postpartum: Occurrence and Correlates.Maternal and child health journal · 2016Article
- Well-Being and Diabetes Management in Early Pregnant Women with Type 1 Diabetes Mellitus.International journal of environmental research and public health · 2016Article
- A best practice position statement on pregnancy in chronic kidney disease: the Italian Study Group on Kidney and Pregnancy.Journal of nephrology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type 1 diabetes mellitus in pregnant women increases the risk of adverse outcomes for mother and offspring. Careful preconception counselling and screening is important, with particular focus on glycaemic control, indications for antihypertensive therapy, screening for diabetic nephropathy, diabetic retinopathy and thyroid dysfunction, as well as review of other medications. Supplementation with folic acid should be initiated before conception in order to minimize the risk of fetal malformations. Obtaining and maintaining tight control of blood glucose and blood pressure before and during pregnancy is crucial for optimizing outcomes; however, the risk of severe hypoglycaemia during pregnancy is a major obstacle. Although pregnancy does not result in deterioration of kidney function in women with diabetic nephropathy and normal serum creatinine levels, pregnancy complications such as pre-eclampsia and preterm delivery are more frequent in these women than in women with T1DM and normal kidney function. Rapid-acting insulin analogues are considered safe to use in pregnancy and studies on long-acting insulin analogues have provided reassuring results. Immediately after delivery the insulin requirement declines to approximately 60% of the prepregnancy dose, and remains 10% lower than before pregnancy during breastfeeding.
Indexed as
Identifiers
22965164What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.