ReviewNature reviews. Endocrinology2012
Rate of neonatal weight gain and effects on adult metabolic health.
Review in Nature reviews. Endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- International Consensus Guideline on Small for Gestational Age: Etiology and Management From Infancy to Early Adulthood.Endocrine reviews · 2023Guideline
- Effect of maternal n-3 long-chain polyunsaturated fatty acid supplementation during pregnancy and/or lactation on adiposity in childhood: a systematic review and meta-analysis of randomized controlled trials.European journal of clinical nutrition · 2014Pooled it
- Infant hyperglycemic excursions by saliva 1,5-anhydroglucitol varied by weight status, rapid weight gain, and mode of feeding: an exploratory secondary analysis.The American journal of clinical nutrition · 2026Trial
- The Impact of Rapid Growth After Retardation at the First 1000 Days of Life (FDLs) on the Risk of Noncommunicable Diseases in Indonesian Adolescence.International journal of pediatrics · 2025Article
- Effects of different embryo culture media on birthweight following assisted reproductive technology.Human reproduction open · 2025Article
- Prepuberty is a window period for curcumin to prevent obesity in postnatal overfed rats.Pediatric research · 2024Article
- Cerebral white matter hyperintensities in adults born small for gestational age at 12 years after cessation of childhood growth hormone treatment: a prospective cohort study including untreated controls.EClinicalMedicine · 2024Article
- Late preterm birth and growth trajectories during childhood: a linked retrospective cohort study.BMC pediatrics · 2023Article
- Growth of twins conceived using assisted reproductive treatments up to 5 years old: a national growth cohort.Human reproduction (Oxford, England) · 2023Article
- Comparison of the cardiometabolic profiles of adolescents conceived through ART with those of a non-ART cohort.Human reproduction (Oxford, England) · 2022Observational
- Influence of gestational diabetes mellitus on lipid signatures in breast milk and association with fetal physical development.Frontiers in nutrition · 2022Article
- Association Between Fat Mass in Early Life and Later Fat Mass Trajectories.JAMA pediatrics · 2020Article
- The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents.European journal of epidemiology · 2020Article
- Relapsing 6q24-related transient neonatal diabetes mellitus with insulin resistance: A case report.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2020Article
- Current Insights into the Role of the Growth Hormone-Insulin-Like Growth Factor System in Short Children Born Small for Gestational Age.Hormone research in paediatrics · 2019Review
- The growth of assisted reproductive treatment-conceived children from birth to 5 years: a national cohort study.BMC medicine · 2018Article
- Preterm Birth: Long Term Cardiovascular and Renal Consequences.Current pediatric reviews · 2018Review
- Longitudinal fat mass and visceral fat during the first 6 months after birth in healthy infants: support for a critical window for adiposity in early life.Pediatric obesity · 2017Article
- Impact of Early Infant Growth, Duration of Breastfeeding and Maternal Factors on Total Body Fat Mass and Visceral Fat at 3 and 6 Months of Age.Annals of nutrition & metabolism · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association of rapid weight gain in early life with increased adiposity and obesity in later life has been established, whereas whether rapid neonatal weight gain predisposes individuals to other risk factors for cardiovascular disease and type 2 diabetes mellitus remains controversial. Gain in weight of >0.5 SD scores in the first 3 months of life (described as rapid weight gain) is associated with an unfavourable health profile in adulthood, and keeping weight gain below this threshold could reduce the risk of cardiovascular and metabolic diseases later in life. Weight gain above this threshold is not necessarily unhealthy if the increase is in proportion with the increase in length. As such, regular measurement of both the weight and length of all infants is important. Preterm infants and those who are born small for gestational age are most likely to have rapid weight gain, and are high-risk populations for unfavourable health profiles in adulthood.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.