Evidence mapPaperPMID 2305711Full record

ArticleThe American journal of clinical nutrition1990

A new predictive equation for resting energy expenditure in healthy individuals.

M D Mifflin, S T St Jeor, L A Hill, B J Scott, S A Daugherty, Y O Koh

9 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in The American journal of clinical nutrition, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 942 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
942citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02798744 phase4completedstarted 2016, after this paper: background citation

SGLT-2 Inhibitor Empagliflozin Effects on Appetite and Weight Regulation: A Randomised Double-blind Placebo-controlled Trial (The SEESAW Study)

Ran2016Enrolled68Registered outcomes15Posted comparisons0ConditionsDiabetes Mellitus, Type 2Armsdiet, empagliflozin, Placebo
Open the trial in the graph
NCT00005177 completednot on this map

Reno Diet Heart Study

TypeobservationalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran1985 to 1996ConditionsCardiovascular Diseases, Heart Diseases, Obesity
NCT02734238 phase4completednot on this mapstarted 2016, after this paper: background citation

Physiological and Psychological Effects of Testosterone During Severe Energy Deficit and Recovery: a Randomized, Placebo Controlled Trial

TypeinterventionalSponsorPennington Biomedical Research CenterRan2016 to 2017Enrolled53ConditionsCaloric Restriction, ExerciseArmsSesame Oil, testosterone enanthate
NCT04478565 completednot on this mapstarted 2016, after this paper: background citation

Development of Alternatives for the Estimation of the Resting Metabolic Rate From Anthropometric Variables in Paralympic Athletes

TypeobservationalSponsorIberoamerican Institute of Sports Science and Human MovementRan2016 to 2016Enrolled15ConditionsResting Metabolic Rate, Disability Physical, Athletic InjuriesArmsIndirect Calorimetry
NCT04887584 nacompletednot on this mapstarted 2022, after this paper: background citation

Identifying the Role of Pulses in a Healthful Diet: Metabolomic Signatures of Dietary Pulses and Their Benefits on Cardiometabolic Risk Factors

TypeinterventionalSponsorUSDA, Western Human Nutrition Research CenterRan2022 to 2023Enrolled20ConditionsBody WeightArmsControl diet, Low Pulse diet, High Pulse diet
NCT05394779 nacompletednot on this mapstarted 2022, after this paper: background citation

Evaluation of Performance and Safety of DTXO App, an Innovative Digital Therapy, in Improving Weight Loss and Weight-Loss Maintenance of Patients With Obesity by Increasing Their Adherence to Dietary, Exercise Regimens and Psycho-Behavioral Program

TypeinterventionalSponsorAdvice Pharma Group srlRan2022 to 2024Enrolled246ConditionsObesity, Health Behavior, Life Style, Dietary HabitsArmsDTXO APP, PLACEBO APP - Control group
NCT06890546 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Nigella Sativa Oil Supplementation and Dietary Intervention on Lipid Profile in Overweight Adults with Hyperlipidemia: a Randomized Controlled Clinical Trial

TypeinterventionalSponsorIstanbul Bilgi UniversityRan2023 to 2025Enrolled64ConditionsHyperlipidaemia, HyperlipidemiaArmsNigella Sativa Oil capsule, Diet
NCT07229963 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Postprandial Cardiometabolic Effects of Interrupting Sedentary Behavior With Exercise of Varying Intensity in Healthy Overweight Adults

TypeinterventionalSponsorHacettepe UniversityRan2025 to 2026Enrolled16ConditionsCardiovascular Risk Markers, Substrate Oxidation, Postprandial Metabolism, Exercise PhysiologyArmsAerobic Exercise Intervention, Sprint Exercise Intervention, Sedentary Behaviour Intervention
NCT07403929 narecruitingnot on this mapstarted 2026, after this paper: background citation

Determination of the Effect of Fermented Grape Juice Consumption on Oxidative Stress and Inflammation Biomarkers and SIRT-1 Levels in Fibromyalgia Patients

TypeinterventionalSponsorHacettepe UniversityRan2026 to 2027Enrolled45ConditionsFibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome, PrimaryArmsMedical Nutrition Therapy (MNT), Hardaliye (200 mL/day)
3 · Its place in the literature

Who cites it

942 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The effects of enteral tube feeding on nutrition, survival, and quality of life outcomes in advanced upper gastrointestinal cancers: a systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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882 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M D MifflinNutrition Education and Research Program, University of Nevada School of Medicine, Reno 89557.
S T St Jeor
L A Hill
B J Scott
S A Daugherty
Y O Koh

Funding

WEIGHT TRENDS, BEHAVIORS AND CVD: NORMALS VS OBESER01HL034589 · UNIVERSITY OF NEVADA RENO · 1985 to 1994
NHLBI NIH HHS HL 34589NIADDK NIH HHS AM07478
6 · The paper itself

Abstract

A predictive equation for resting energy expenditure (REE) was derived from data from 498 healthy subjects, including females (n = 247) and males (n = 251), aged 19-78 y (45 +/- 14 y, mean +/- SD). Normal-weight (n = 264) and obese (n = 234) individuals were studied and REE was measured by indirect calorimetry. Multiple-regression analyses were employed to drive relationships between REE and weight, height, and age for both men and women (R2 = 0.71): REE = 9.99 x weight + 6.25 x height - 4.92 x age + 166 x sex (males, 1; females, 0) - 161. Simplification of this formula and separation by sex did not affect its predictive value: REE (males) = 10 x weight (kg) + 6.25 x height (cm) - 5 x age (y) + 5; REE (females) = 10 x weight (kg) + 6.25 x height (cm) - 5 x age (y) - 161. The inclusion of relative body weight and body-weight distribution did not significantly improve the predictive value of these equations. The Harris-Benedict Equations derived in 1919 overestimated measured REE by 5% (p less than 0.01). Fat-free mass (FFM) was the best single predictor of REE (R2 = 0.64): REE = 19.7 x FFM + 413. Weight also was closely correlated with REE (R2 = 0.56): REE = 15.1 x weight + 371.

Indexed as

Energy MetabolismAdultAgedBody HeightBody WeightCalorimetry, IndirectFemaleHumansMaleMiddle AgedRegression AnalysisSkinfold Thickness

Identifiers

PMID2305711

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.