Evidence map›Paper›PMID 23195437›Full record

ReviewCurrent opinion in cell biology2013

Post-translational modification and regulation of actin.

Jonathan R Terman, Anna Kashina

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 213 citations in OpenAlex.

  1. Alterations of actin in aging.Journal of cell science · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. In Vitro Analysis of Profilin 1 Binding to Recombinant Actin.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Immunohistochemical Study onActa histochemica et cytochemica · 2025
    Review
  11. Review
  12. Review
  13. Review
  14. Molecular Regulation of Cardiomyocyte Maturation.Current cardiology reports · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jonathan R TermanDepartment of Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. jonathan.terman@utsouthwestern.edu
Anna Kashina
The University of Texas Southwestern Medical Center · USUniversity of Pennsylvania · US

Funding

Molecular Mechanisms of Semaphorin/Plexin-mediated Cytoskeletal ReorganizationR01NS073968 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI TERMAN, JONATHAN R · 2011 to 2022
$3.5M
Role of Protein Arginylation in Cardiovascular DevelopmentR01HL084419 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KASHINA, ANNA S · 2007 to 2011
$2.2M
NHLBI NIH HHS R01 HL084419NHLBI NIH HHS R01HL084419NINDS NIH HHS NS073968NINDS NIH HHS R01 NS073968
6 · The paper itself

Abstract

Many of the best-studied actin regulatory proteins use non-covalent means to modulate the properties of actin. Yet, actin is also susceptible to covalent modifications of its amino acids. Recent work is increasingly revealing that actin processing and its covalent modifications regulate important cellular events. In addition, numerous pathogens express enzymes that specifically use actin as a substrate to regulate their hosts' cells. Actin post-translational alterations have been linked to different normal and disease processes and the effects associated with metabolic and environmental stressors. Herein, we highlight specific co-translational and post-translational modifications of actin and discuss the current understanding of the role that these modifications play in regulating actin.

Indexed as

Protein Processing, Post-TranslationalAcetylationActinsADP Ribose TransferasesAnimalsGlycosylationHumansMethylationOxidation-ReductionSumoylationUbiquitinationActinsADP Ribose Transferases

Identifiers

PMID23195437
PMCPMC3578039
OpenAlexW2018917950

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.