Evidence map›Paper›PMID 23200723›Full record

ReviewCurrent opinion in cell biology2013

Taking a cellular road-trip: mRNA transport and anchoring.

Catherine A Pratt, Kimberly L Mowry

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  12. Review
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  16. Article
  17. RNA binding proteins in the regulation of heart development.The international journal of biochemistry & cell biology · 2013
    Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Catherine A PrattDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA.
Kimberly L Mowry

Funding

RNA Localization in Xenopus OocytesR01GM071049 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 2005 to 2018
$4.2M
NIGMS NIH HHS GM071049NIGMS NIH HHS R01 GM071049
6 · The paper itself

Abstract

mRNA localization is a crucial mechanism for post-transcriptional control of gene expression used in numerous cellular contexts to generate asymmetric enrichment of an encoded protein. This process has emerged as a fundamental regulatory mechanism that operates in a wide range of organisms to control an array of cellular processes. Recently, significant advances have been made in our understanding of the mechanisms that regulate several steps in the mRNA localization pathway. Here we discuss the progress made in understanding localization element recognition, paying particular attention to the role of RNA structure. We also consider the function of mRNP granules in mRNA transport, as well as new results pointing to roles for the endocytic pathway in mRNA localization.

Indexed as

RNA TransportAnimalsEndocytosisEukaryotic CellsHumansNucleic Acid ConformationRibonucleoproteinsRNA, Messengermessenger ribonucleoproteinRibonucleoproteinsRNA, Messenger

Identifiers

PMID23200723
PMCPMC3583371

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.