ReviewCurrent atherosclerosis reports2013
The rationale for initiating treatment of hypercholesterolemia in young adulthood.
Review in Current atherosclerosis reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- There is urgent need to treat atherosclerotic cardiovascular disease risk earlier, more intensively, and with greater precision: A review of current practice and recommendations for improved effectiveness.American journal of preventive cardiology · 2022Review
- Nutritional Treatment in a Cohort of Pediatric Patients with Familial Hypercholesterolaemia: Effect on Lipid Profile.Nutrients · 2022Article
- Should We Be Screening for Ischaemic Heart Disease Earlier in Childhood?Children (Basel, Switzerland) · 2022Review
- American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease.Circulation · 2022Article
- Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.European heart journal · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Even though it has been recognized for some time that the lesions of atherosclerosis begin in childhood, there has been reluctance to recommend intervention, especially intervention with drugs, before the age of 50 years. Recent evidence, particularly evidence from human genetics, has greatly strengthened the case for earlier intervention to correct hypercholesterolemia and other risk factors. This report briefly reviews some of the emerging lines of evidence that are helping us reach a consensus on when and how we should intervene.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.