Evidence map›Paper›PMID 23284048›Full record

ReviewCold Spring Harbor perspectives in biology2013

Endoreplication.

Norman Zielke, Bruce A Edgar, Melvin L DePamphilis

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Endocrine gland growth as the developmental switch for insect diapause.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Norman ZielkeDeutsches Krebsforschungszentrum (DKFZ)-Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH) Allianz, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany. n.zielke@DKFZ-heidelberg.de
Bruce A Edgar
Melvin L DePamphilis

Funding

Initiation Of DNA Replication In Mammalian ChromosomesZIAHD000506 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI DEPAMPHILIS, MELVIN · 2009 to 2023
$15.4M
Gene Expression At The Beginning Of Mammalian DevelopmentZIAHD000507 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI DEPAMPHILIS, MELVIN · 2009 to 2018
$8.6M
Growth Regulation during Drosophila DevelopmentR01GM051186 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ROHRSCHNEIDER, LARRY RAY · 1994 to 2011
$5.2M
INITIATION OF DNA REPLICATION IN MAMMILIAN CHROMOSOMESZ01HD000506 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI DEPAMPHILIS, MELVIN · 1996 to 2008
$1.7M
Intramural NIH HHS Z01 HD000506NIGMS NIH HHS GM51186NIGMS NIH HHS R01 GM051186
6 · The paper itself

Abstract

Developmentally programmed polyploidy occurs by at least four different mechanisms, two of which (endoreduplication and endomitosis) involve switching from mitotic cell cycles to endocycles by the selective loss of mitotic cyclin-dependent kinase (CDK) activity and bypassing many of the processes of mitosis. Here we review the mechanisms of endoreplication, focusing on recent results from Drosophila and mice.

Indexed as

AnimalsCell CycleCyclin-Dependent Kinase 2Cyclin EDNA ReplicationDrosophilaEndoreduplicationMicePolyploidyCyclin-Dependent Kinase 2Cyclin E

Identifiers

PMID23284048
PMCPMC3579398

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.