Evidence mapPaperPMID 23341675Full record

Trial reportCanadian family physician Medecin de famille canadien2013

Assessment of the Siksika chronic disease nephropathy-prevention clinic.

David R R Ward, Ellen Novak, Nairne Scott-Douglas, Sony Brar, Melvin White, Brenda R Hemmelgarn

Abstract readClinical Trial
In one paragraph

Trial report in Canadian family physician Medecin de famille canadien, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

David R R WardDepartment of Medicine, University of Calgary, Alberta.
Ellen Novak
Nairne Scott-Douglas
Sony Brar
Melvin White
Brenda R Hemmelgarn
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if a community-based multifactorial intervention clinic led by a nurse practitioner would improve management of First Nations people at risk of developing chronic kidney disease.

designQualitative descriptive study.

settingA nephropathy-prevention clinic in Siksika Nation, Alta.

participantsFirst Nations people with diabetes, hypertension, or dyslipidemia who were referred to the clinic.

main outcome measuresChanges in blood pressure (BP), hemoglobin A(1c), and low-density lipoprotein levels, as well as in use of antiplatelet therapy, angiotensin-converting enzyme inhibitor or angiotensin receptor blocker medications, and statin therapy.

resultsMembers of the Siksika Nation were treated according to clinical practice guidelines. A total of 78 patients had at least 2 visits to the clinic and were included in this analysis (61.5% were women; mean age 56 years). Among those initially above target, a significant reduction was achieved in mean hemoglobin A(1c) (0.96%; P < .01), systolic BP (15.84 mm Hg; P < .05), diastolic BP (7.16 mm Hg; P < .001), and low-density lipoprotein (0.62 mmol/L; P < .01) levels. There was a significant increase in the proportion of patients with clinical indications who were treated with acetylsalicylic acid (42.4%; P < .01), angiotensin-converting enzyme inhibitor or angiotensin receptor blocker medications (35.9%; P < .01), or statin therapy (35.9%; P < .01).

conclusionA community-based, nurse practitioner-led clinic can improve many clinically relevant factors in patients at risk of developing chronic kidney disease. Studies have shown that achieving treatment targets is associated with a reduced risk of early death and cardiovascular events; the effect in the First Nations population on these hard clinical end points remains to be determined.

Indexed as

Indians, North AmericanPractice Patterns, Nurses'AdultAgedAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAspirinBlood PressureCanadaDiabetes MellitusDiabetic NephropathiesDyslipidemiasFemaleGlycated HemoglobinHumansHydroxymethylglutaryl-CoA Reductase InhibitorsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAspirinGlycated Hemoglobinhemoglobin A1c protein, humanHydroxymethylglutaryl-CoA Reductase InhibitorsLipoproteins, LDLPlatelet Aggregation Inhibitors

Identifiers

PMID23341675
PMCPMC3555674
OpenAlexW2112620884

What Socratic holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.