ArticlePloS one2013
Morphology and nanomechanics of sensory neurons growth cones following peripheral nerve injury.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 35 citations in OpenAlex.
- Morphological and nanomechanical insights into the selective targeting of breast cancer cells by novel nickel ferrite nanoparticles.Scientific reports · 2026Article
- Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development.Theranostics · 2022Review
- Role of Non-coding RNAs in Axon Regeneration after Peripheral Nerve Injury.International journal of biological sciences · 2022Review
- Multiscale Mechanobiology in Brain Physiology and Diseases.Frontiers in cell and developmental biology · 2022Review
- Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing.Journal of experimental & clinical cancer research : CR · 2021Article
- Effects of green light photobiomodulation on Dental Pulp Stem Cells: enhanced proliferation and improved wound healing by cytoskeleton reorganization and cell softening.Lasers in medical science · 2021Article
- Nano-scientific Application of Atomic Force Microscopy in Pathology: from Molecules to Tissues.International journal of medical sciences · 2020Review
- Myotube elasticity of an amyotrophic lateral sclerosis mouse model.Scientific reports · 2018Article
- Electrophysiologic alterations in the excitability of the sciatic and vagus nerves during early stages of sepsis.Journal of pain research · 2018Article
- Atomic force microscopy as an advanced tool in neuroscience.Translational neuroscience · 2015Review
- Heavy ion and X-ray irradiation alter the cytoskeleton and cytomechanics of cortical neurons.Neural regeneration research · 2014Article
- Morphology and intrinsic excitability of regenerating sensory and motor neurons grown on a line micropattern.PloS one · 2014Article
- Neuron biomechanics probed by atomic force microscopy.International journal of molecular sciences · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re-growth. Our differential interference contrast microscopy and immunocytochemistry results show that conditioned axotomy, induced by sciatic nerve injury, did not increase somatic size of adult lumbar sensory neurons from mice dorsal root ganglia sensory neurons but promoted the appearance of larger neurites and growth cones. Using atomic force microscopy on live neurons, we investigated whether membrane mechanical properties of growth cones of axotomized neurons were modified following sciatic nerve injury. Our data revealed that neurons having a regenerative growth were characterized by softer growth cones, compared to control neurons. The increase of the growth cone membrane elasticity suggests a modification in the ratio and the inner framework of the main structural proteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.