ReviewEuropean journal of heart failure2013
Heart failure in elderly patients: distinctive features and unresolved issues.
Review in European journal of heart failure, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05760157 (To Establish a Multimodal Dynamic Risk Assessment System of Heart Failure in Patients With Myocardial Infarction Based on Coronary Microcirculation.), which is not on this map. Cited by 87 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
To Establish a Multimodal Dynamic Risk Assessment System of Heart Failure in Patients With Myocardial Infarction Based on Coronary Microcirculation.
Who cites it
87 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Survival benefit of guideline-directed medical therapy in older patients with heart failure: a systematic review and meta-analysis.Heart (British Cardiac Society) · 2026Pooled it
- Effectiveness of transitional care program in older adults with heart failure: a systematic review and meta-analysis of randomised controlled trials.BMC geriatrics · 2026Pooled it
- Efficacy and safety of vutrisiran in transthyretin amyloid cardiomyopathy across the age spectrum: The HELIOS-B trial.European journal of heart failure · 2025Trial
- Finerenone Improves Outcomes in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction Irrespective of Age: A Prespecified Analysis of FINEARTS-HF.Circulation. Heart failure · 2024Trial
- Why do older adults decline participation in research? Results from two deprescribing clinical trials.Trials · 2023Trial
- Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997.European journal of heart failure · 2018Trial
- Trial
- Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF.European heart journal · 2015Trial
- Fibroblast Growth Factor 23 and Outcomes in Acute Heart Failure.Biomolecules · 2026Article
- Integrated drug management for elderly patients with congestive heart failure: enhancing medication accuracy using the MINE (Medicine IN gEriatric) application.Journal of geriatric cardiology : JGC · 2026Article
- Plasma CA125 as a Prognostic Marker in Very Elderly Patients Hospitalized for Acute Heart Failure.Journal of clinical medicine · 2026Article
- The AHEAD-NLR score: a novel inflammatory-comorbidity integrated tool for predicting long-term mortality in patients with heart failure after acute myocardial infarction.Scientific reports · 2026Article
- Real-world data on early initiation of sodium-glucose co-transporter-2 inhibitors in newly diagnosed heart failure with reduced ejection fraction.ESC heart failure · 2026Article
- Finerenone in mildly reduced or preserved ejection fraction and chronic kidney disease: a narrative review.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Review
- LVEF-based phenotyping in very old adults hospitalised for heart failure: cardiological discrimination, shared geriatric burden, and treatment gaps.Frontiers in cardiovascular medicine · 2026Article
- An individual treatment effect approach to predict response to mineralocorticoid receptor antagonists in patients with heart failure and reduced ejection fraction.European journal of heart failure · 2025Article
- Burden and etiology of heart failure in mainland China from 1990 to 2021: Results from the GBD 2021 study.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Enhanced Multi-Model Machine Learning-Based Dementia Detection Using a Data Enrichment Framework: Leveraging the Blessing of Dimensionality.Bioengineering (Basel, Switzerland) · 2025Article
- Albumin-Bilirubin (ALBI) Score Predicts Long-Term Survival in Elderly Patients with Decompensated Heart Failure.Journal of clinical medicine · 2025Article
- Diastolic dysfunction in primary care: medical and nursing interlocutions.Revista brasileira de enfermagem · 2025Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The prevalence of heart failure (HF) increases with age. While clinical trials suggest that contemporary evidence-based HF therapies have reduced morbidity and mortality, these trials largely excluded the elderly. Questions remain regarding the clinical characteristics of elderly HF patients and the impact of contemporary therapies on their outcomes. This review presents the epidemiology of HF in the elderly and summarizes the data on the pathophysiology of the ageing heart. The clinical characteristics, treatment patterns, and outcomes of elderly HF patients are explored. Finally, the main gaps regarding HF therapies in the elderly and the opportunities for future trials are highlighted.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.