Evidence mapPaperPMID 23622135Full record

ReviewGastroenterology2013

The epidemiology of pancreatitis and pancreatic cancer.

Dhiraj Yadav, Albert B Lowenfels

12 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 12 registered trials, which are not on this map. Cited by 914 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
914citing papers in PubMed, 7 pooled it
98.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06827002 phase1 / phase2active not recruitingstarted 2023, after this paper: background citation

Cissus Quadrangularis (CQR-300®) and Dichrostachys Glomerata (Dyglomera®) Extracts Increase GLP-1 Levels and Inhibit Dipeptidyl Phosphate-4 Activity in Healthy Overweight and Obese Adults

Ran2023Enrolled248Registered outcomes8Posted comparisons0ConditionsAppetite Regulation, Obesity and OverweightArmsCissus quadrangularia, Dextrin, Dichrostachys glomerata, Semaglutide (Rybelsus®)
Open the trial in the graph
NCT02108509 completednot on this mapstarted 2014, after this paper: background citation

Bone Disease in Chronic Pancreatitis: A Complex Phenomenon

TypeobservationalSponsorUniversity of NebraskaRan2014 to 2018Enrolled55ConditionsChronic Pancreatitis, Osteopenia, Osteoporosis
NCT02602574 unknown statusnot on this mapstarted 2018, after this paper: background citation

Endoscopic Retrograde Cholangiopancreatography (ERCP)-Induced and Non-ERCP Induced Acute Pancreatitis: Two Distinct Clinical and Immunological Entities?

TypeobservationalSponsorUniversity Hospital RijekaRan2018 to 2024Enrolled66ConditionsPost-ERCP Acute PancreatitisArmsheparinized peripheral venous blood and urine sample.
NCT02673541 naterminatednot on this mapstarted 2016, after this paper: background citation

Randomized, Multi-Center, Comparative and Cost Effectiveness Study of a Lumen- Apposing, Covered, Self-Expanding Metal Stent (Axios™) Versus Multiple Double Pigtail Stents in the Management of Walled Off Pancreatic Necrosis

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2016 to 2017Enrolled5ConditionsPancreatic NecrosisArmsAXIOS™ stent, Double Pigtail Stents
NCT03112759 nacompletednot on this mapstarted 2017, after this paper: background citation

Assessing the Utility of Cognitive Behavioral Therapy for Pain Control in Patients With Chronic Pancreatitis

TypeinterventionalSponsorUniversity of LouisvilleRan2017 to 2020Enrolled9ConditionsChronic PancreatitisArmsCognitive Behavioral Therapy
NCT03115918 nacompletednot on this mapstarted 2016, after this paper: background citation

Randomized Trial Examining the Impact of Pancreatic Duct Stent Placement in Patients With Acute Necrotizing Pancreatitis in the Prevention of Walled-off Necrosis

TypeinterventionalSponsorAdventHealthRan2016 to 2020Enrolled1ConditionsNecrotizing Pancreatitis, Walled Off NecrosisArmsPancreatic Duct Stent Placement, No Pancreatic Duct Stent Placement
NCT03117556 nawithdrawnnot on this mapstarted 2017, after this paper: background citation

Bilateral Thoracoscopic Splanchnicectomy for Pain Relief in Patients With Unresectable Pancreatic Cancer

TypeinterventionalSponsorUniversity of LouisvilleRan2017 to 2018Enrolled0ConditionsUnresectable Pancreatic CancerArmsBilateral Thoracoscopic Splanchnicectomy
NCT04113499 nacompletednot on this mapstarted 2019, after this paper: background citation

A Randomized Trial Comparing Direct Endoscopic Necrosectomy vs. Step-up Transluminal Endoscopic Interventions in Infected Necrotizing Pancreatitis (DESTIN)

TypeinterventionalSponsorAdventHealthRan2019 to 2022Enrolled11ConditionsPancreatic Necrosis, Necrosis PancreasArmsDirect Endoscopic Intervention, Step-up Endoscopic Intervention
NCT04932785 naunknown statusnot on this mapstarted 2021, after this paper: background citation

To Assess the Comparative Efficacy of Full Calorie Regular Diet (RD) Versus Clear Liquid Diet (CLD) on Length of Hospital Stay (LOHS) for Mild to Moderate Acute Pancreatitis (AP)

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2021 to 2024Enrolled150ConditionsPancreatitis, Diet, Food, and Nutrition, Diet, Pancreatic DiseaseArmsRegular diet, Clear Liquid Diet
NCT04964648 unknown statusnot on this mapstarted 2021, after this paper: background citation

The Validity of Shear Wave Elastography in Diagnosis of Inflammatory and Malignant Pancreatic Diseases

TypeobservationalSponsorAssiut UniversityRan2021 to 2023Enrolled100ConditionsShear Wave Elastography, Pancreatic DiseasesArmsshear wave elastography
NCT05498961 completednot on this mapstarted 2022, after this paper: background citation

The Effect of Gallstone Characteristics for the Severity of Acute Gallstone Pancreatitis

TypeobservationalSponsorHepatopancreatobiliary Surgery Institute of Gansu ProvinceRan2022 to 2023Enrolled301ConditionsAcute Gallstone PancreatitisArmsGallstone characteristics
NCT06553651 narecruitingnot on this mapstarted 2026, after this paper: background citation

Necrosectomy With Cryotechnology for Accelerated Removal

TypeinterventionalSponsorChristopher C. Thompson, MD, MScRan2026 to 2029Enrolled20ConditionsPancreatic Necrosis, Acute Pancreatitis, Acute Pancreatic Necrosis, NecrosisArmsCryotechnology Necrosectomy Procedure
3 · Its place in the literature

Who cites it

914 citing papers in PubMed, 7 syntheses or guidelines pooled it, 1,926 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Non-specific uptake ofScientific reports · 2024
    Trial
  9. Article
  10. Article
  11. Role of cathepsin B in spontaneous pancreatitis in T7D23A trypsinogen mutant mice.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Health Inequities in Pancreatic Disorders in the Black/African American Community.Journal of racial and ethnic health disparities · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Article

854 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Dhiraj YadavDivision of Gastroenterology & Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA. yadavd@upmc.edu
Albert B Lowenfels
New York Medical College · USUniversity of Pittsburgh Medical Center · US

Funding

NIDDK NIH HHS R01 DK077906
6 · The paper itself

Abstract

Acute pancreatitis is one of the most frequent gastrointestinal causes of hospital admission in the United States. Chronic pancreatitis, although lower in incidence, significantly reduces patients' quality of life. Pancreatic cancer is associated with a high mortality rate and is one of the top 5 causes of death from cancer. The burden of pancreatic disorders is expected to increase over time. The risk and etiology of pancreatitis differ with age and sex, and all pancreatic disorders affect the black population more than any other race. Gallstones are the most common cause of acute pancreatitis, and early cholecystectomy eliminates the risk of future attacks. Alcohol continues to be the single most important risk factor for chronic pancreatitis. Smoking is an independent risk factor for acute and chronic pancreatitis, and its effects could synergize with those of alcohol. Significant risk factors for pancreatic cancer include smoking and non-O blood groups. Alcohol abstinence and smoking cessation can alter the progression of pancreatitis and reduce recurrence; smoking cessation is the most effective strategy to reduce the risk of pancreatic cancer.

Indexed as

AdultAgedAge FactorsAlcohol DrinkingFemaleHumansIncidenceMaleMiddle AgedPancreatic NeoplasmsPancreatitisPancreatitis, AlcoholicPrevalencePrognosisRacial GroupsRisk Factors

Identifiers

PMID23622135
PMCPMC3662544
OpenAlexW1977379410

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

and 6 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.