Evidence map›Paper›PMID 23684445›Full record

ReviewCurrent opinion in immunology2013

Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells.

Yacine Bounab, Andrew Getahun, John C Cambier, Marc Daëron

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Mechanisms of central tolerance for B cells.Nature reviews. Immunology · 2017
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yacine BounabInstitut Pasteur, Département d'Immunologie, Centre d'Immunologie Humaine, Paris, France.
Andrew Getahun
John C Cambier
Marc Daëron
National Jewish Health · USInserm · FRInstitut Pasteur · FR

Funding

THE REGULATION OF V ALPHA 7 EXPRESSING T CELLSP01AI022295 · NIAID · NATIONAL JEWISH HEALTH · PI REFAELI, YOSEF · 1985 to 2011
$11.7M
Infectious Agents and B Cell AnergyR01AI077597 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CAMBIER, JOHN C · 2010 to 2014
$1.9M
B Cells and Type 1 DiabetesR01DK096492 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI CAMBIER, JOHN C · 2012 to 2016
$1.6M
Mouse modeling of a human STING gene variant for infectious diseaseR21AI099346 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CAMBIER, JOHN C · 2012 to 2013
$410k
NIAID NIH HHS P01 AI022295NIAID NIH HHS P01AI022295NIAID NIH HHS R01 AI077597NIAID NIH HHS R01AI077597NIAID NIH HHS R01AI097346NIAID NIH HHS R21 AI099346NIAID NIH HHS R21AI099346NIDDK NIH HHS R01 DK096492
6 · The paper itself

Abstract

Recent progress has begun to reveal the often complex and changing roles of phosphotyrosine and phosphoinositide phosphatases in regulation of immunoreceptor signaling. The resultant confusion has been further increased by discoveries of new players. Here we provide a review of recent progress in defining the roles of these enzymes in immunoreceptor-dependent mast cell, T cell and B cell activation.

Indexed as

Signal TransductionAnimalsB-LymphocytesHumansMast CellsPhosphoric Monoester HydrolasesReceptors, ImmunologicT-LymphocytesPhosphoric Monoester HydrolasesReceptors, Immunologic

Identifiers

PMID23684445
PMCPMC3732051
OpenAlexW2004402341

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.