ReviewOxidative medicine and cellular longevity2013
Assessment of endothelial dysfunction in childhood obesity and clinical use.
Review in Oxidative medicine and cellular longevity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 58 citations in OpenAlex.
- Supportive treatment of vascular dysfunction in pediatric subjects with obesity: the OBELIX study.Nutrition & diabetes · 2022Trial
- Article
- Serum FAM132A/Adipolin correlates with endothelial dysfunction in children with obesity.Pediatric research · 2026Article
- Non-Alcoholic Fatty Liver Disease and Coronary Artery Disease: A Bidirectional Association Based on Endothelial Dysfunction.International journal of molecular sciences · 2024Review
- Nonalcoholic fatty liver disease is an independent risk factor for ischemic stroke after revascularization in patients with Moyamoya disease: a prospective cohort study.Lipids in health and disease · 2024Article
- Chronotropic incompetence is more frequent in obese adolescents and relates to systemic inflammation and exercise intolerance.Journal of sport and health science · 2023Article
- Cardiorespiratory fitness and development of childhood cardiovascular risk: The EXAMIN YOUTH follow-up study.Frontiers in physiology · 2023Article
- Relationship of Endothelial Microparticles to Obesity and Cardiovascular Disease Risk in Children and Adolescents.Journal of the American Heart Association · 2022Article
- Multiple non-invasive peripheral vascular function parameters with obesity and cardiometabolic risk indicators in school-aged children.BMC pediatrics · 2022Article
- Proposition of Cutoff Points for Anthropometric Indicators to Identify High Blood Pressure in Adolescents.Frontiers in nutrition · 2022Article
- Predictive Markers of Early Cardiovascular Impairment and Insulin Resistance in Obese Pediatric Patients.Diagnostics (Basel, Switzerland) · 2021Article
- Visceral Obesity and High Systolic Blood Pressure as the Substrate of Endothelial Dysfunction in Obese Adolescents.Arquivos brasileiros de cardiologia · 2021Article
- Feasibility and Tolerance of Fingertip Peripheral Arterial Tonometry Measurements in School-Aged Children.Frontiers in pediatrics · 2021Article
- Body Composition and Physical Fitness Affect Central Hemodynamics in Young Children.Frontiers in pediatrics · 2021Article
- Effect of bariatric surgery before pregnancy on the vascular function in the offspring: protocol of a cross-sectional follow-up study.BMJ paediatrics open · 2019Article
- Targeting Endothelial Function to Treat Heart Failure with Preserved Ejection Fraction: The Promise of Exercise Training.Oxidative medicine and cellular longevity · 2017Review
- Longitudinal Associations of Leptin and Adiponectin with Heart Rate Variability in Children.Frontiers in physiology · 2017Article
- Childhood obesity-related endothelial dysfunction: an update on pathophysiological mechanisms and diagnostic advancements.Pediatric research · 2016Review
- Endothelial dysfunction in inflammatory bowel diseases: Pathogenesis, assessment and implications.World journal of gastroenterology · 2016Review
- Childhood adiposity: being male is a potential cardiovascular risk factor.European journal of pediatrics · 2016Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association of obesity with noncommunicable diseases, such as cardiovascular complications and diabetes, is considered a major threat to the management of health care worldwide. Epidemiological findings show that childhood obesity is rapidly rising in Western society, as well as in developing countries. This pandemic is not without consequences and can affect the risk of future cardiovascular disease in these children. Childhood obesity is associated with endothelial dysfunction, the first yet still reversible step towards atherosclerosis. Advanced research techniques have added further insight on how childhood obesity and associated comorbidities lead to endothelial dysfunction. Techniques used to measure endothelial function were further brought to perfection, and novel biomarkers, including endothelial progenitor cells, were discovered. The aim of this paper is to provide a critical overview on both in vivo as well as in vitro markers for endothelial integrity. Additionally, an in-depth description of the mechanisms that disrupt the delicate balance between endothelial damage and repair will be given. Finally, the effects of lifestyle interventions and pharmacotherapy on endothelial dysfunction will be reviewed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.