Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2013
Lifestyle interventions and independence for elders study: recruitment and baseline characteristics.
Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01072500 (The LIFE Study - Lifestyle Interventions and Independence for Elders), which is not on this map. Cited by 87 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The LIFE Study - Lifestyle Interventions and Independence for Elders
Who cites it
87 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.
- Effective Interventions on Improving Elderly's Independence in Activity of Daily Living: A Systematic Review and Logic Model.Frontiers in public health · 2020Pooled it
- Success and cost-effectiveness of strategies to recruit older adults to a behavioral intervention research study.Contemporary clinical trials · 2025Trial
- Physical activity and mobility disability in older adult cancer survivors.JNCI cancer spectrum · 2025Trial
- Effects of a Physical Activity Intervention on Perceived Stress, Fatigue, and Depressive Symptoms in Older Adults: A Secondary Analysis of the LIFE Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Trial
- A comparison of two mail-based strategies to recruit older cancer survivors into a randomized controlled trial of a lifestyle intervention.Journal of cancer survivorship : research and practice · 2022Trial
- Recruitment and Screening Methods in Alzheimer's Disease Research: The FIT-AD Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Trial
- Recruitment methods and yield rates in a clinical trial of physical exercise for older adults with hypertension-HAEL Study: a study within a trial.BMC medical research methodology · 2022Trial
- Metabolic syndrome and the benefit of a physical activity intervention on lower-extremity function: Results from a randomized clinical trial.Experimental gerontology · 2021Trial
- Three-Year, Postintervention, Follow-up Comparison of Health Care Resource Utilization and Costs in the Lifestyle Interventions and Independence for Elders (LIFE) Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Trial
- The Tribulations of Trials: Lessons Learnt Recruiting 777 Older Adults Into REtirement in ACTion (REACT), a Trial of a Community, Group-Based Active Aging Intervention Targeting Mobility Disability.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- Comparative Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Response to a Physical Activity Intervention in Older Adults: Results From the Lifestyle Interventions and Independence for Elders Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- Comparison of Recruitment Strategies for Engaging Older Minority Adults: Results From Take Heart.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- Association of Fish Oil and Physical Activity on Mobility Disability in Older Adults.Medicine and science in sports and exercise · 2020Trial
- Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability.Journal of the American Geriatrics Society · 2020Trial
- The Enabling Reduction of Low-Grade Inflammation in Seniors (ENRGISE) Pilot Study: Screening Methods and Recruitment Results.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Trial
- Effect of Hospitalizations on Physical Activity Patterns in Mobility-Limited Older Adults.Journal of the American Geriatrics Society · 2019Trial
- Self-Reported Physical Function As a Predictor of Hospitalization in the Lifestyle Interventions and Independence for Elders Study.Journal of the American Geriatrics Society · 2018Trial
- Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.Journal of the American Geriatrics Society · 2018Trial
- Maintenance of Physical Function 1 Year After Exercise Intervention in At-Risk Older Adults: Follow-up From the LIFE Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018Trial
- Evaluating Accelerometry Thresholds for Detecting Changes in Levels of Moderate Physical Activity and Resulting Major Mobility Disability.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018Trial
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundRecruitment of older adults into long-term clinical trials involving behavioral interventions is a significant challenge. The Lifestyle Interventions and Independence for Elders (LIFE) Study is a Phase 3 multicenter randomized controlled multisite trial, designed to compare the effects of a moderate-intensity physical activity program with a successful aging health education program on the incidence of major mobility disability (the inability to walk 400 m) in sedentary adults aged 70-89 years, who were at high risk for mobility disability (scoring ≤ 9 on the Short Physical Performance Battery) at baseline.
methodsRecruitment methods, yields, efficiency, and costs are described together with a summary of participant baseline characteristics. Yields were examined across levels of sex, race and ethnicity, and Short Physical Performance Battery, as well as by site.
resultsThe 21-month recruiting period resulted in 14,812 telephone screens; 1,635 participants were randomized (67.2% women, 21.0% minorities, 44.7% with Short Physical Performance Battery scores ≤ 7). Of the telephone-screened participants, 37.6% were excluded primarily because of regular participation in physical activity, health exclusions, or self-reported mobility disability. Direct mailing was the most productive recruitment strategy (59.5% of randomized participants). Recruitment costs were $840 per randomized participant. Yields differed by sex and Short Physical Performance Battery. We accrued 11% more participant follow-up time than expected during the recruitment period as a result of the accelerated recruitment rate.
conclusionsThe LIFE Study achieved all recruitment benchmarks. Bulk mailing is an efficient method for recruiting high-risk community-dwelling older persons (including minorities), from diverse geographic areas for this long-term behavioral trial.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.