ArticleFrontiers in endocrinology2013
Effects of bariatric surgery on adipokine-induced inflammation and insulin resistance.
Article in Frontiers in endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of the Treatment With Dapagliflozin and Metformin Compared to Metformin Monotherapy for Weight Loss on Diabetic and Prediabetic Patients With Obesity Class III
Single Anastomosis Duodeno Jejunal Bypass With Sleeve Gastrectomy (SADJB-SG) Versus Intensive Medical Therapy (IMT) in the Treatment of Type 2 Diabetes Mellitus Among Asian Patients With BMI 23.5 - 30 kg/m2: A Clinical Trial
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Effect of bariatric surgery on glycemic and metabolic outcomes in people with obesity and type 2 diabetes mellitus: a systematic review, meta-analysis, and meta-evidence of 39 studies.Frontiers in nutrition · 2025Pooled it
- Impact of Bariatric Surgery on Hypoglossal Nerve Stimulation Outcomes.The Laryngoscope · 2026Article
- ANGPTL8 is upregulated in subcutaneous adipose tissue at early term after bariatric surgery in patients living with obesity.European journal of clinical investigation · 2026Article
- An immediate post op and follow up assessment of circulating adipo-cytokines after bariatric surgery in morbid obesity.Metabolism open · 2022Article
- Changes in adipokine levels and metabolic profiles following bariatric surgery.BMC endocrine disorders · 2022Article
- Determinants of type 2 diabetes remission after bariatric surgery in obese Japanese patients: a retrospective cohort study.Diabetology international · 2021Article
- Browning white adipose tissue using adipose stromal cell-targeted resveratrol-loaded nanoparticles for combating obesity.Journal of controlled release : official journal of the Controlled Release Society · 2021Article
- The Links of Ghrelin to Incretins, Insulin, Glucagon, and Leptin After Bariatric Surgery.Frontiers in genetics · 2021Article
- Changes of Urinary Cytokines in Non-Diabetic Obese Patients After Laparoscopic Sleeve Gastrectomy.International journal of general medicine · 2021Article
- Serum Adipocytokines Levels and Their Association with Insulin Sensitivity in Morbidly Obese Individuals Undergoing Bariatric Surgery.Journal of obesity & metabolic syndrome · 2020Article
- A retrospective case control study identifies peripheral blood mononuclear cell albumin RNA expression as a biomarker for non-alcoholic fatty liver disease.Langenbeck's archives of surgery · 2020Article
- Mechanisms Underlying Type 2 Diabetes Remission After Metabolic Surgery.Frontiers in endocrinology · 2019Review
- Short-Term Impact of Laparoscopic Sleeve Gastrectomy on Serum Cartonectin and Vaspin Levels in Obese Subjects.Obesity surgery · 2018Article
- Macrophage functions in lean and obese adipose tissue.Metabolism: clinical and experimental · 2017Review
- Implication of Ceramide Kinase in Adipogenesis.Mediators of inflammation · 2017Article
- Adipokine Pattern After Bariatric Surgery: Beyond the Weight Loss.Obesity surgery · 2016Review
- Recent advances in the modification of taste and food preferences following bariatric surgery.Reviews in endocrine & metabolic disorders · 2016Review
- Long-term Effect of Ileal Transposition on Adipokine Serum Level in Zucker (Orl)-Lepr(fa) Fatty Rats.Obesity surgery · 2015Article
- Obesity-related immune responses and their impact on surgical outcomes.International journal of obesity (2005) · 2015Review
- Clinical potential of resistin as a novel prognostic biomarker for cellulitis.Experimental and therapeutic medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over a third of the US population is obese and at high risk for developing type 2 diabetes, insulin resistance, and other metabolic disorders. Obesity is considered a chronic low-grade inflammatory condition that is primarily attributed to expansion and inflammation of adipose tissues. Indeed, adipocytes produce and secrete numerous proinflammatory and anti-inflammatory cytokines known as adipokines. When the balance of these adipokines is shifted toward higher production of proinflammatory factors, local inflammation within adipose tissues and subsequently systemic inflammation occur. These adipokines including leptin, visfatin, resistin, apelin, vaspin, and retinol binding protein-4 can regulate inflammatory responses and contribute to the pathogenesis of diabetes. These effects are mediated by key inflammatory signaling molecules including activated serine kinases such as c-Jun N-terminal kinase and serine kinases inhibitor κB kinase and insulin signaling molecules including insulin receptor substrates, protein kinase B (PKB, also known as Akt), and nuclear factor kappa B. Bariatric surgery can decrease body weight and improve insulin resistance in morbidly obese subjects. However, despite reports suggesting reduced inflammation and weight-independent effects of bariatric surgery on glucose metabolism, mechanisms behind such improvements are not yet well understood. This review article focuses on some of these novel adipokines and discusses their changes after bariatric surgery and their relationship to insulin resistance, fat mass, inflammation, and glucose homeostasis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.